INT210832

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Context Info
Confidence 0.01
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0
Pain Relevance 0.06

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (Abca4) ATPase activity (Abca4) transmembrane transport (Abca4)
Abca4 (Mus musculus)
Pain Link Frequency Relevance Heat
Potency 10 60.12 Quite High
Neuropeptide 2 32.48 Quite Low
agonist 26 5.00 Very Low Very Low Very Low
5HT 4 5.00 Very Low Very Low Very Low
Opioid 4 5.00 Very Low Very Low Very Low
antagonist 4 5.00 Very Low Very Low Very Low
Analgesic 2 5.00 Very Low Very Low Very Low
Inflammation 2 5.00 Very Low Very Low Very Low
Morphine 2 5.00 Very Low Very Low Very Low
mu opioid receptor 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 4 10.88 Low Low
Obesity 26 5.00 Very Low Very Low Very Low
Body Weight 10 5.00 Very Low Very Low Very Low
Targeted Disruption 6 5.00 Very Low Very Low Very Low
Loss Of Sense Of Smell 2 5.00 Very Low Very Low Very Low
Cancer 2 5.00 Very Low Very Low Very Low
INFLAMMATION 2 5.00 Very Low Very Low Very Low
Overweight 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Surprisingly, a 2-h exposure to increasing concentrations of the synthetic ligand THIQ did not cause sequestration of either wild-type MC4R, Rm1, or Rm2 (Fig. 6A, B, C), even though similar concentrations of THIQ activated both Rm1 and Rm2 as measured by cAMP accumulation (Fig. 3).
Positive_regulation (activated) of Rm1
1) Confidence 0.01 Published 2007 Journal PLoS ONE Section Body Doc Link PMC1930153 Disease Relevance 0 Pain Relevance 0.03
Surprisingly, a 2-h exposure to increasing concentrations of the synthetic ligand THIQ did not cause sequestration of either wild-type MC4R, Rm1, or Rm2 (Fig. 6A, B, C), even though similar concentrations of THIQ activated both Rm1 and Rm2 as measured by cAMP accumulation (Fig. 3).
Positive_regulation (activated) of Rm2
2) Confidence 0.01 Published 2007 Journal PLoS ONE Section Body Doc Link PMC1930153 Disease Relevance 0 Pain Relevance 0.03

General Comments

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