INT210862

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Context Info
Confidence 0.34
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.42
Pain Relevance 0.17

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (POMC, Mc4r) small molecule metabolic process (POMC) signal transducer activity (Mc4r)
cell-cell signaling (POMC) cytoplasm (POMC) extracellular space (POMC)
POMC (Homo sapiens)
Mc4r (Mus musculus)
Pain Link Frequency Relevance Heat
agonist 26 92.08 High High
5HT 4 87.32 High High
Potency 10 67.52 Quite High
mu opioid receptor 2 18.08 Low Low
Morphine 2 14.12 Low Low
Analgesic 2 13.76 Low Low
Immobilon 2 9.72 Low Low
opioid receptor 2 5.40 Low Low
Opioid 4 5.00 Very Low Very Low Very Low
antagonist 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Obesity 26 100.00 Very High Very High Very High
Targeted Disruption 6 52.56 Quite High
Body Weight 10 5.00 Very Low Very Low Very Low
Disease 4 5.00 Very Low Very Low Very Low
Loss Of Sense Of Smell 2 5.00 Very Low Very Low Very Low
Cancer 2 5.00 Very Low Very Low Very Low
INFLAMMATION 2 5.00 Very Low Very Low Very Low
Overweight 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
-MSH have delineated a role for MC4R in these processes [19].
MSH Binding (role) of MC4R
1) Confidence 0.34 Published 2007 Journal PLoS ONE Section Body Doc Link PMC1930153 Disease Relevance 0.17 Pain Relevance 0.12
-MSH analog MT-II as a potential treatment for obesity [36] and is approximately 30-fold more potent at MC4R than ?
MSH Binding (potent) of MC4R associated with obesity
2) Confidence 0.28 Published 2007 Journal PLoS ONE Section Body Doc Link PMC1930153 Disease Relevance 0.25 Pain Relevance 0.05

General Comments

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