INT210899

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Context Info
Confidence 0.39
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 3.31
Pain Relevance 0.11

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (SELE) cell adhesion (SELE) plasma membrane (SELE)
SELE (Homo sapiens)
IGHD1-14 (Homo sapiens)
SELE - S128R (1)
Pain Link Frequency Relevance Heat
Inflammation 2 81.20 Quite High
cytokine 2 77.92 Quite High
Potency 2 65.28 Quite High
Inflammatory marker 2 22.32 Low Low
drug abuse 2 5.00 Very Low Very Low Very Low
Angina 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Diabetes Mellitus 124 100.00 Very High Very High Very High
Coronary Artery Disease 106 100.00 Very High Very High Very High
Insulin Resistance 2 97.44 Very High Very High Very High
Adhesions 8 93.60 High High
Nicotine Addiction 2 88.56 High High
Hypertension 2 87.16 High High
INFLAMMATION 4 81.20 Quite High
Cardiovascular Disease 4 77.20 Quite High
Disease 22 67.36 Quite High
Obesity 2 24.80 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In particular, the S128R polymorphism (SNP rs5361) of the E-selectin gene has been associated with CAD, premature CAD, as well as type 2 diabetes mellitus (DM2).
E-selectin gene Binding (associated) of DM2 associated with coronary artery disease and diabetes mellitus
1) Confidence 0.39 Published 2007 Journal BMC Med Genet Section Body Doc Link PMC1933415 Disease Relevance 1.62 Pain Relevance 0.08
The present study investigated possible interaction between DM2 and the E-selectin S128R polymorphism in predisposing individuals to acquiring CAD, using a large homogenous Saudi population as a study model.
E-selectin (S128R) Binding (interaction) of DM2 associated with coronary artery disease and diabetes mellitus
2) Confidence 0.33 Published 2007 Journal BMC Med Genet Section Body Doc Link PMC1933415 Disease Relevance 1.69 Pain Relevance 0.03

General Comments

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