INT2109

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Context Info
Confidence 0.41
First Reported 1977
Last Reported 2009
Negated 0
Speculated 0
Reported most in Abstract
Documents 4
Total Number 4
Disease Relevance 0.89
Pain Relevance 0.66

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (LIF) extracellular region (LIF)
Anatomy Link Frequency
lymphocytes 4
epithelial cells 2
LIF (Homo sapiens)
Pain Link Frequency Relevance Heat
aspirin 5 99.60 Very High Very High Very High
cytokine 60 97.16 Very High Very High Very High
agonist 2 81.76 Quite High
endometriosis 2 80.24 Quite High
anesthesia 3 75.00 Quite High
cINOD 1 75.00 Quite High
Inflammation 14 54.40 Quite High
Inflammatory mediators 8 5.00 Very Low Very Low Very Low
analgesia 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Injury 3 86.60 High High
Reprotox - General 3 7 85.80 High High
Male Infertility 2 84.72 Quite High
Polycystic Ovary Syndrome 2 81.88 Quite High
Endometriosis (extended) 2 80.24 Quite High
INFLAMMATION 23 75.00 Quite High
Small Cell Lung Carcinoma 1 56.68 Quite High
Malignant Neoplastic Disease 4 55.24 Quite High
Leukemia 7 50.00 Quite Low
Lung Cancer 16 48.64 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
A review of LIF immunolabeling in stages of luteal phase
Negative_regulation (review) of Gene_expression (immunolabeling) of LIF
1) Confidence 0.41 Published 2009 Journal Reprod Biol Endocrinol Section Body Doc Link PMC2675529 Disease Relevance 0.49 Pain Relevance 0.04
Fibroblasts exhibited a prominent LIF response and a several-fold higher activation of ERK relative to STAT3 by IL-6 cytokines (Fig. 1A, bottom panel), in contrast to normal epithelial cells.
Negative_regulation (exhibited) of Gene_expression (response) of LIF in epithelial cells associated with cytokine
2) Confidence 0.31 Published 2005 Journal BMC Cancer Section Body Doc Link PMC1289280 Disease Relevance 0.11 Pain Relevance 0.22
LIF production of lymphocytes was inhibited by INDO, ASA, PhB, CHINOIN 127 and CHINOIN 105.
Negative_regulation (inhibited) of Gene_expression (production) of LIF in lymphocytes associated with aspirin
3) Confidence 0.26 Published 1986 Journal Acta Med Hung Section Abstract Doc Link 3295745 Disease Relevance 0.13 Pain Relevance 0.33
The experimental results show decrease of LIF production after operation in 6 individuals and reduction of eletrophoretic mobility of PMN and lymphocytes.
Negative_regulation (decrease) of Gene_expression (production) of LIF in lymphocytes
4) Confidence 0.10 Published 1977 Journal G Batteriol Virol Immunol Section Abstract Doc Link 350684 Disease Relevance 0.16 Pain Relevance 0.07

General Comments

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