INT211112

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Context Info
Confidence 0.28
First Reported 2007
Last Reported 2008
Negated 0
Speculated 1
Reported most in Body
Documents 3
Total Number 5
Disease Relevance 4.28
Pain Relevance 0.92

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Etn1 (Mus musculus)
Pain Link Frequency Relevance Heat
Etanercept 112 100.00 Very High Very High Very High
cva 174 98.68 Very High Very High Very High
rheumatoid arthritis 44 98.60 Very High Very High Very High
Hippocampus 4 83.76 Quite High
Opioid 2 67.44 Quite High
Regional anesthesia 4 31.92 Quite Low
methotrexate 45 23.44 Low Low
antagonist 3 10.68 Low Low
Arthritis 17 5.00 Very Low Very Low Very Low
anesthesia 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Mycobacterial Infection 9 99.92 Very High Very High Very High
Air Embolism 160 98.84 Very High Very High Very High
Rheumatoid Arthritis 49 98.60 Very High Very High Very High
Stress 2 94.80 High High
Heart Rate Under Development 17 92.80 High High
Pressure And Volume Under Development 6 92.00 High High
Sprains And Strains 212 89.92 High High
Cv Unclassified Under Development 12 86.24 High High
Opportunistic Infections 3 81.68 Quite High
Histoplasma Infection 2 80.24 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In the first phase, probes derived from known ERV sequences were used to screen the B6 assembled genome and a collection of ETn/MusD or IAP elements in B6 was obtained.
Positive_regulation (collection) of ETn
1) Confidence 0.28 Published 2008 Journal PLoS Genetics Section Body Doc Link PMC2265474 Disease Relevance 0.29 Pain Relevance 0
Another gene for which significant differences in expression correlate with presence of an ETn element is Opcml.
Positive_regulation (presence) of ETn element
2) Confidence 0.24 Published 2008 Journal PLoS Genetics Section Body Doc Link PMC2265474 Disease Relevance 0.68 Pain Relevance 0.15
Since the expected incidence of TB in the USA is 6–8/100 000 patient-years, it is unclear whether TB is increased in ETN-treated patients over the general RA population.
Spec (whether) Positive_regulation (increased) of ETN associated with mycobacterial infection, rheumatoid arthritis and etanercept
3) Confidence 0.02 Published 2007 Journal Therapeutics and Clinical Risk Management Section Body Doc Link PMC1936291 Disease Relevance 1.53 Pain Relevance 0.18
Emission spectrometry can also be used to detect increased ETN2 levels indicative of venous air embolism as an alternative to mass spectrometers, and may be a more sensitive detector (0.1 mL/kg) (54).


Positive_regulation (increased) of ETN2 associated with cva and air embolism
4) Confidence 0.01 Published 2008 Journal Journal of Korean Medical Science Section Body Doc Link PMC2580000 Disease Relevance 0.92 Pain Relevance 0.30
Increased ETN2 in a patient ventilated with denitrogenated gas has been considered as a specific sign of venous air embolism (54).
Positive_regulation (Increased) of ETN2 associated with cva and air embolism
5) Confidence 0.01 Published 2008 Journal Journal of Korean Medical Science Section Body Doc Link PMC2580000 Disease Relevance 0.86 Pain Relevance 0.30

General Comments

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