INT211135

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Context Info
Confidence 0.23
First Reported 2007
Last Reported 2007
Negated 1
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 2.14
Pain Relevance 2.14

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (MTX1)
MTX1 (Homo sapiens)
Pain Link Frequency Relevance Heat
rheumatoid arthritis 77 100.00 Very High Very High Very High
methotrexate 69 100.00 Very High Very High Very High
Arthritis 50 100.00 Very High Very High Very High
psoriasis 60 99.12 Very High Very High Very High
cINOD 4 98.24 Very High Very High Very High
Adalimumab 231 96.56 Very High Very High Very High
spinal inflammation 24 90.48 High High
Infliximab 23 66.36 Quite High
Etanercept 11 64.88 Quite High
antagonist 24 64.40 Quite High
Disease Link Frequency Relevance Heat
Rheumatoid Arthritis 78 100.00 Very High Very High Very High
Seronegative Spondarthritis 44 100.00 Very High Very High Very High
Psoriasis 69 99.12 Very High Very High Very High
INFLAMMATION 16 97.76 Very High Very High Very High
Low Back Pain 28 90.48 High High
Disease 44 86.88 High High
Arthritis 9 59.48 Quite High
Disease Progression 4 43.16 Quite Low
Necrosis 6 29.04 Quite Low
Cancer 8 28.68 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Patients (n=313) were stratified according to MTX use (yes or no) and extent of psoriasis involvement (?
Positive_regulation (according) of Neg (no) Localization (yes) of MTX associated with psoriasis and methotrexate
1) Confidence 0.23 Published 2007 Journal Therapeutics and Clinical Risk Management Section Body Doc Link PMC1936294 Disease Relevance 1.23 Pain Relevance 1.18
The use of MTX in PsA is facultative, and, in RA patients not taking concomitant MTX, the dosing frequency can be increased to 40 mg every week to obtain additional benefit.
Positive_regulation (increased) of Localization (use) of MTX associated with rheumatoid arthritis, methotrexate and arthritis
2) Confidence 0.10 Published 2007 Journal Biologics : Targets & Therapy Section Body Doc Link PMC2721299 Disease Relevance 0.91 Pain Relevance 0.96

General Comments

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