INT211265
From wiki-pain
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Sentences Mentioned In
Key: | Protein | Mutation | Event | Anatomy | Negation | Speculation | Pain term | Disease term |
On the other hand, HK-II expression in high grade hepatocellular carcinoma (HCC) is elevated likely a result of upregulation caused by low levels of Glut-1 on the cell surface. | |||||||||||||||
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The value of PET/CT has been questioned for detection of intrahepatic disease because of the high background activity in the liver parenchyma due to high glucose metabolism and abundant expression of Glut-1 and hexokinase II (HK-II). | |||||||||||||||
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This suggests that it is the retention of FDG in malignant cells (as determined by Glut-1 and HK-II expression) rather than clearance of blood pool activity that is the most important factor in delayed lesion detection. | |||||||||||||||
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