INT211286

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Context Info
Confidence 0.17
First Reported 2007
Last Reported 2010
Negated 0
Speculated 1
Reported most in Body
Documents 5
Total Number 5
Disease Relevance 2.57
Pain Relevance 0.37

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
NK cells 2
T cells 2
Trav6-3 (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 109 98.40 Very High Very High Very High
Inflammation 79 79.84 Quite High
rheumatoid arthritis 39 79.68 Quite High
Potency 1 74.04 Quite High
chemokine 12 5.00 Very Low Very Low Very Low
Arthritis 12 5.00 Very Low Very Low Very Low
Inflammatory response 7 5.00 Very Low Very Low Very Low
cINOD 4 5.00 Very Low Very Low Very Low
Crohn's disease 4 5.00 Very Low Very Low Very Low
Infliximab 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Lymphatic System Cancer 95 99.20 Very High Very High Very High
Apoptosis 112 96.72 Very High Very High Very High
Death 29 92.76 High High
T-cell Lymphoma 11 86.40 High High
Acquired Immune Deficiency Syndrome Or Hiv Infection 3 84.72 Quite High
Mycobacterial Infection 3 84.00 Quite High
Autoimmune Disease 6 81.92 Quite High
INFLAMMATION 75 79.84 Quite High
Rheumatoid Arthritis 39 79.68 Quite High
Systemic Lupus Erythematosus 3 77.68 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Lymphomas were characterized by FACS in order to determine the expression of CD4, CD8, the TCR?
Spec (determine) Regulation (determine) of Spec (determine) Gene_expression (expression) of TCR associated with lymphatic system cancer
1) Confidence 0.17 Published 2010 Journal PLoS ONE Section Body Doc Link PMC3008744 Disease Relevance 0.68 Pain Relevance 0
However, the proliferative responses of T cells to TCR engagement shown in Figure 2 indicated that the TCR?
Regulation (responses) of Gene_expression (engagement) of TCR in T cells
2) Confidence 0.12 Published 2007 Journal Blood Section Body Doc Link PMC1939810 Disease Relevance 0.08 Pain Relevance 0.26
The events leading to the down-regulation of TCR/CD3 complex expression on serial ligation by peptide/MHC complexes are well documented.12 Less well understood are the molecular mechanisms for the sustained down-regulation of TCR?
Regulation (regulation) of Gene_expression (expression) of TCR
3) Confidence 0.12 Published 2007 Journal Blood Section Body Doc Link PMC1939810 Disease Relevance 0.56 Pain Relevance 0.04
is rate-limiting, thereby regulating the amount of TCR/CD3 complex expressed at the cell surface.8,9 In NK cells, the TCR?
Regulation (regulating) of Gene_expression (expressed) of TCR in NK cells
4) Confidence 0.07 Published 2007 Journal Blood Section Body Doc Link PMC1939810 Disease Relevance 0 Pain Relevance 0
Furthermore, however speculative, the deletion within the TCR-?
Regulation (speculative) of Gene_expression (deletion) of TCR
5) Confidence 0.04 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2440804 Disease Relevance 1.26 Pain Relevance 0.06

General Comments

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