INT211296

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Context Info
Confidence 0.13
First Reported 2007
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.32
Pain Relevance 0.31

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
synovial joints 2
Trav6-3 (Mus musculus)
Pain Link Frequency Relevance Heat
rheumatoid arthritis 13 98.86 Very High Very High Very High
chemokine 5 98.24 Very High Very High Very High
cytokine 40 86.08 High High
Inflammation 26 65.64 Quite High
Inflammatory response 3 41.08 Quite Low
Multiple sclerosis 5 11.60 Low Low
Neuritis 24 5.00 Very Low Very Low Very Low
Peripheral nervous system 5 5.00 Very Low Very Low Very Low
Arthritis 4 5.00 Very Low Very Low Very Low
methotrexate 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Rheumatoid Arthritis 13 98.86 Very High Very High Very High
Autoimmune Disease 9 95.00 High High
INFLAMMATION 29 65.64 Quite High
Targeted Disruption 19 63.08 Quite High
Syndrome 19 50.00 Quite Low
Disorder Of Lipid Metabolism 6 50.00 Quite Low
Disease 20 37.28 Quite Low
Multiple Sclerosis 6 11.60 Low Low
Experimental Autoimmune Neuritis 24 5.00 Very Low Very Low Very Low
Cytomegalovirus Infection 6 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Migration of PBLs could be further enhanced by the addition of CXCL-10, CCL5, or CXCL-12 to the lower chamber, chemokines known to be up-regulated in RA synovial joints (Figure 6C).29 Subset analysis revealed enhanced migration of TCR?
Positive_regulation (enhanced) of TCR Binding (migration) of in synovial joints associated with chemokine and rheumatoid arthritis
1) Confidence 0.13 Published 2007 Journal Blood Section Body Doc Link PMC1939810 Disease Relevance 0.10 Pain Relevance 0.21
Upon TCR ligation, they respond rapidly to secrete high levels of IFN-?
Positive_regulation (respond) of TCR Binding (ligation) of
2) Confidence 0.10 Published 2010 Journal Journal of Biomedicine and Biotechnology Section Body Doc Link PMC2825561 Disease Relevance 0.22 Pain Relevance 0.10

General Comments

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