INT211304

Context Info Confidence 0.11 First Reported 2007 Last Reported 2010 Negated 0 Speculated 0 Reported most in Body Documents 2 Total Number 2 Disease Relevance 0.76 Pain Relevance 0.03

Trav6-3 (Mus musculus)

Pain Link Frequency Relevance Heat rheumatoid arthritis 13 56.24 Inflammation 14 22.32 cytokine 28 5.00 chemokine 4 5.00 Arthritis 4 5.00 Inflammatory response 2 5.00 methotrexate 1 5.00 anesthesia 1 5.00 withdrawal 1 5.00 cINOD 1 5.00

Disease Link Frequency Relevance Heat Infection 27 75.12 Influenza Virus Infection 54 72.64 Acquired Immune Deficiency Syndrome Or Hiv Infection 1 61.28 Mycobacterial Infection 1 60.56 Autoimmune Disease 2 58.48 Rheumatoid Arthritis 13 56.24 Systemic Lupus Erythematosus 1 54.24 Solid Tumor 1 51.28 Hematologic Neoplasms 1 50.00 Sprains And Strains 3 31.28

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

RIII (CD16).10,11 In light of these crucial functions the TCR?

Negative_regulation (functions) of TCR Binding (light) of

1) Confidence 0.11 Published 2007 Journal Blood Section Body Doc Link PMC1939810 Disease Relevance 0.34 Pain Relevance 0.03

Even a single conserved residue replacement at position 7 (D-E7) completely abolished the productive interaction between the TCR and the variant NP366/Db ligands, as observed in the case of the Taiwan-NP366/Db ligand (Table S1).

Negative_regulation (abolished) of TCR Binding (interaction) of

2) Confidence 0.06 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2868023 Disease Relevance 0.42 Pain Relevance 0

General Comments

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