INT211308

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Context Info
Confidence 0.19
First Reported 2007
Last Reported 2010
Negated 0
Speculated 1
Reported most in Body
Documents 3
Total Number 4
Disease Relevance 0.30
Pain Relevance 0.31

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell adhesion (Cd4) plasma membrane (Cd4) enzyme binding (Cd4)
Anatomy Link Frequency
T cells 2
Cd4 (Mus musculus)
Cd8a (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 63 86.16 High High
tolerance 15 65.76 Quite High
Inflammation 26 45.20 Quite Low
rheumatoid arthritis 13 5.00 Very Low Very Low Very Low
anesthesia 4 5.00 Very Low Very Low Very Low
chemokine 4 5.00 Very Low Very Low Very Low
Arthritis 4 5.00 Very Low Very Low Very Low
Inflammatory response 3 5.00 Very Low Very Low Very Low
withdrawal 2 5.00 Very Low Very Low Very Low
Bile 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cytomegalovirus Infection 6 96.64 Very High Very High Very High
Autoimmune Disease 18 59.04 Quite High
Lymphocytic Choriomeningitis 1 55.36 Quite High
Sprains And Strains 9 50.00 Quite Low
Hyperglycemia 4 48.96 Quite Low
INFLAMMATION 29 45.20 Quite Low
Infection 6 42.72 Quite Low
Diabetes Mellitus 15 22.64 Low Low
Immune System Diseases 1 6.16 Low Low
Disease 27 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
However, the finding that IL-2 deficient mice are able to mount primary CD8+ T cell responses and that CD4+ T cells condition DC, through CD40L/CD40 interactions, to efficiently prime CD8+ T cells disfavored the original hypothesis [33], [34], [35], [45].
CD4 Binding (interactions) of CD8 in T cells
1) Confidence 0.19 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2939396 Disease Relevance 0.06 Pain Relevance 0.06
Antibodies were purchased from BD Pharmingen or eBioscience and included monoclonal antibodies recognizing mouse CD4 (RM4-5), CD8?
CD4 Binding (recognizing) of CD8
2) Confidence 0.11 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2853576 Disease Relevance 0.06 Pain Relevance 0.04
(TIA2-PE), together with anti-CD3, anti-CD4, or anti-CD8 conjugated to PerCP and analyzed by flow cytometry.
CD4 Spec (analyzed) Binding (conjugated) of CD8
3) Confidence 0.02 Published 2007 Journal Blood Section Body Doc Link PMC1939810 Disease Relevance 0.19 Pain Relevance 0.13
Both CD4+, and CD8+ T-cells and the ratio of CD4+/CD8+ did not seem to be affected by LcZhang (Data not shown).


CD4 Binding (ratio) of CD8 in T-cells
4) Confidence 0.02 Published 2008 Journal BMC Immunol Section Body Doc Link PMC2596084 Disease Relevance 0 Pain Relevance 0.07

General Comments

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