INT211545

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Context Info
Confidence 0.42
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.38
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Lpin1) endoplasmic reticulum (Lpin1) nucleus (Lpin1)
lipid metabolic process (Lpin1) cytoplasm (Lpin1)
Lpin1 (Mus musculus)
Pain Link Frequency Relevance Heat
isoflurane 4 5.00 Very Low Very Low Very Low
imagery 4 5.00 Very Low Very Low Very Low
Bile 2 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Fatty Liver 2 86.00 High High
Hyperlipidemia 6 82.28 Quite High
Lipodystrophy 4 81.84 Quite High
Disorder Of Lipid Metabolism 8 58.00 Quite High
Stress 2 6.64 Low Low
Hematological Disease 12 5.00 Very Low Very Low Very Low
Anaemia 10 5.00 Very Low Very Low Very Low
Sprains And Strains 6 5.00 Very Low Very Low Very Low
Cancer 4 5.00 Very Low Very Low Very Low
Immunotherapy Of Cancer 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In Kit mutants, a defective hepatic metabolism, with the abnormal low expression of VldlR and Lpin1, leads to the maintenance of this "transient steatosis".
Negative_regulation (metabolism) of Gene_expression (expression) of Lpin1
1) Confidence 0.42 Published 2007 Journal BMC Dev Biol Section Body Doc Link PMC1940254 Disease Relevance 0.13 Pain Relevance 0
Lpin1 reduced expression is presumably a major event leading to the abnormal metabolism of lipid in KitSco5/Sco5 mice.
Negative_regulation (reduced) of Gene_expression (expression) of Lpin1
2) Confidence 0.42 Published 2007 Journal BMC Dev Biol Section Body Doc Link PMC1940254 Disease Relevance 0.25 Pain Relevance 0

General Comments

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