INT211567

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Context Info
Confidence 0.09
First Reported 2007
Last Reported 2010
Negated 0
Speculated 1
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.55
Pain Relevance 0.05

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (LIPC) extracellular region (LIPC)
Anatomy Link Frequency
bile 1
LIPC (Homo sapiens)
Pain Link Frequency Relevance Heat
Bile 1 95.40 Very High Very High Very High
Angina 2 5.00 Very Low Very Low Very Low
isoflurane 2 5.00 Very Low Very Low Very Low
imagery 2 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
alcohol 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disorder Of Lipid Metabolism 267 99.90 Very High Very High Very High
Lipodystrophy 2 91.68 High High
Hematological Disease 6 65.24 Quite High
Coronary Artery Disease 15 39.80 Quite Low
Liver Disease 1 28.84 Quite Low
Obesity 1 28.00 Quite Low
Hyperlipidemia 8 5.00 Very Low Very Low Very Low
Anaemia 5 5.00 Very Low Very Low Very Low
Cardiovascular Disease 5 5.00 Very Low Very Low Very Low
Increased Venous Pressure Under Development 5 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
TGs in HDL are hydrolyzed by HL.
Gene_expression (hydrolyzed) of HL associated with disorder of lipid metabolism
1) Confidence 0.09 Published 2010 Journal Lipids Health Dis Section Body Doc Link PMC2920871 Disease Relevance 1.39 Pain Relevance 0
To decipher the molecular basis of Kit-dependent steatosis, we determined the expression profiles of key genes involved in lipid hepatic metabolism: such as apoliproteins (Apoa1, ApoB), lipoprotein receptors (LdlR, VldlR, Scarb1, Lrp1), lipase (Lipc, LipH, Lpl) and others implicated in hepatic lipidogenesis (Scap, Srebf1, Srebf2), lipid secretion (Pltp, Mttp, Abca1), bile acid synthesis (Cyp8b1, Cyp7a1), lipid transport (Slc10a1, Abcb11, Abcb1a, Abcc2) and a lipodystrophy gene, Lipin 1 (Lpin1), encoding a phosphatidate phosphatase enzyme with transcription activity [26-28].
Spec (determined) Gene_expression (expression) of LipH in bile associated with bile and lipodystrophy
2) Confidence 0.07 Published 2007 Journal BMC Dev Biol Section Body Doc Link PMC1940254 Disease Relevance 0.16 Pain Relevance 0.05

General Comments

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