INT211572

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Context Info
Confidence 0.21
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.06
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (Kit, Pik3r1) nucleus (Kit, Pik3r1) plasma membrane (Kit, Pik3r1)
kinase activity (Kit, Pik3r1) cell differentiation (Kit) intracellular (Pik3r1)
Kit (Mus musculus)
Pik3r1 (Mus musculus)
Pain Link Frequency Relevance Heat
isoflurane 2 5.00 Very Low Very Low Very Low
imagery 2 5.00 Very Low Very Low Very Low
Bile 1 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Anaemia 5 56.32 Quite High
Hematological Disease 6 5.00 Very Low Very Low Very Low
Disorder Of Lipid Metabolism 4 5.00 Very Low Very Low Very Low
Sprains And Strains 3 5.00 Very Low Very Low Very Low
Hyperlipidemia 3 5.00 Very Low Very Low Very Low
Lipodystrophy 2 5.00 Very Low Very Low Very Low
Cancer 2 5.00 Very Low Very Low Very Low
Immunotherapy Of Cancer 2 5.00 Very Low Very Low Very Low
Repression 1 5.00 Very Low Very Low Very Low
Fatty Liver 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Interestingly, altering the binding of PI3K with the KIT protein, and reducing the activation of AKT to 10%, does not affect the weight of mutant animals [20], suggesting that, during the post-natal development, the KIT-dependent metabolism of triglycerides is not fully associated with the PI3K pathway but results from another signalling pathway.


KIT protein Binding (binding) of PI3K
1) Confidence 0.21 Published 2007 Journal BMC Dev Biol Section Body Doc Link PMC1940254 Disease Relevance 0.06 Pain Relevance 0

General Comments

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