INT211693

Context Info Confidence 0.04 First Reported 2007 Last Reported 2007 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0 Pain Relevance 0.67

signal transduction (Cntnap1) cell adhesion (Cntnap1) cytoskeleton organization (Cntnap1)

Anatomy Link Frequency nodes 2 Cntnap1 (Rattus norvegicus)

Pain Link Frequency Relevance Heat Nav1.6 80 100.00 unmyelinated 6 54.68 sodium channel 25 50.00 Pain 9 5.00 Neuropathic pain 6 5.00 Inflammation 6 5.00 Demyelination 4 5.00 Peripheral nervous system 3 5.00 Action potential 3 5.00 Multiple sclerosis 2 5.00

Disease Link Frequency Relevance Heat Demyelinating Disease 11 5.00 Pain 10 5.00 Neuropathic Pain 8 5.00 INFLAMMATION 8 5.00 Injury 5 5.00 Nervous System Injury 3 5.00 Peripheral Arterial Disease 3 5.00 Disease 2 5.00 Hyperalgesia 1 5.00 Bites And Stings 1 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Quantitative evaluation of Nav1.6 and caspr immunofluorescence staining intensities and nodal gap axial length within single caspr-identified typical nodes in normal vs. lesioned IONs

Regulation (evaluation) of Regulation (intensities) of caspr in nodes associated with nav1.6

1) Confidence 0.04 Published 2007 Journal BMC Neurosci Section Body Doc Link PMC1941742 Disease Relevance 0 Pain Relevance 0.67

General Comments

This test has worked.