INT211700

Context Info Confidence 0.29 First Reported 2007 Last Reported 2010 Negated 0 Speculated 0 Reported most in Body Documents 5 Total Number 5 Disease Relevance 2.06 Pain Relevance 1.04

isomerase activity (Mri1) nucleus (Mri1) cytoplasm (Mri1)

Anatomy Link Frequency fat 1 T cell 1 Mri1 (Mus musculus)

Pain Link Frequency Relevance Heat imagery 277 100.00 anesthesia 12 95.16 isoflurane 5 81.20 Central nervous system 23 44.68 Inflammation 36 44.52 Multiple sclerosis 7 6.84 ketamine 4 5.00 Spinal cord 3 5.00 withdrawal 3 5.00 Neuritis 3 5.00

Disease Link Frequency Relevance Heat Multiple Sclerosis 53 99.86 Malignant Neoplastic Disease 10 99.04 Breast Cancer 68 98.64 Paralysis 1 93.52 Paraplegia 2 91.72 Paraparesis 1 90.52 Glioma 22 89.60 Fibroadenoma 1 86.04 Cancer 225 84.08 Prostate Cancer 5 73.28

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Subsequently, MRI fat signal was suppressed using a chemical shift-selective (CHESS) pulse to avoid signal contamination and enhance discrimination of the prostate.

Negative_regulation (suppressed) of MRI in fat associated with imagery

1) Confidence 0.29 Published 2007 Journal BMC Urol Section Abstract Doc Link PMC1945027 Disease Relevance 0.07 Pain Relevance 0.35

This report was followed in the same year by the first case report of MRI-guided FUS for treatment of a malignant breast tumour by Huber and colleagues [40].

Negative_regulation (report) of MRI-guided associated with malignant neoplastic disease, breast cancer and imagery

2) Confidence 0.26 Published 2008 Journal Eur Radiol Section Body Doc Link PMC2441491 Disease Relevance 0.90 Pain Relevance 0.24

After induction of EAE, mice underwent cerebral MRI between day 5 and 16 post T cell transfer on a 7 Tesla rodent scanner (Pharmascan 70/16AS, Bruker BioSpin, Ettlingen, Germany), applying a 20 mm RF-Quadrature-Volume head coil.

Negative_regulation (underwent) of MRI in T cell associated with multiple sclerosis and imagery

3) Confidence 0.09 Published 2010 Journal J Neuroinflammation Section Body Doc Link PMC2978145 Disease Relevance 0.65 Pain Relevance 0.22

At this concentration and MRI voxel size of 0.09 mm3 (300 µm×300 µm×1 mm) used in this study, 9 FE-Pro labeled cells would produce detectable MRI signal reduction.

Negative_regulation (reduction) of MRI associated with imagery

4) Confidence 0.09 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2746284 Disease Relevance 0.38 Pain Relevance 0.17

The second block of MRI data was acquired up to 80 minutes after the first series of images.

Negative_regulation (block) of MRI associated with imagery

5) Confidence 0.05 Published 2007 Journal BMC Cancer Section Body Doc Link PMC2241841 Disease Relevance 0.06 Pain Relevance 0.05

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