INT211714

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Context Info
Confidence 0.43
First Reported 2006
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 4
Total Number 4
Disease Relevance 3.77
Pain Relevance 0.52

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (VIM) plasma membrane (VIM) cytoskeleton (VIM)
cytoplasm (VIM)
Anatomy Link Frequency
epithelial cells 2
VIM (Homo sapiens)
Pain Link Frequency Relevance Heat
Infliximab 24 99.68 Very High Very High Very High
rheumatoid arthritis 72 97.08 Very High Very High Very High
spinal inflammation 3 35.12 Quite Low
Sicca syndrome 4 27.76 Quite Low
Arthritis 3 20.24 Low Low
Chronic pancreatitis 10 5.00 Very Low Very Low Very Low
Inflammation 7 5.00 Very Low Very Low Very Low
antagonist 5 5.00 Very Low Very Low Very Low
cytokine 3 5.00 Very Low Very Low Very Low
Immobilon 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Carcinoma 11 99.08 Very High Very High Very High
Cancer 114 98.68 Very High Very High Very High
Adenocarcinoma 9 97.40 Very High Very High Very High
Endometrial Cancer 9 97.20 Very High Very High Very High
Rheumatoid Arthritis 72 97.08 Very High Very High Very High
Disease 16 88.12 High High
Pancreatic Cancer 48 86.72 High High
Metastasis 5 85.04 High High
Skin Cancer 14 76.00 Quite High
Breast Cancer 57 74.12 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Analysis of vimentin expression by 2-D PAGE
Regulation (Analysis) of Gene_expression (expression) of vimentin
1) Confidence 0.43 Published 2006 Journal Biomark Insights Section Body Doc Link PMC2528299 Disease Relevance 0.65 Pain Relevance 0
Vimentin expression was expected since it has also been consistently demonstrated in endometrial adenocarcinomas [8].
Regulation (expected) of Gene_expression (expression) of Vimentin associated with adenocarcinoma
2) Confidence 0.28 Published 2007 Journal Diagn Pathol Section Body Doc Link PMC1947947 Disease Relevance 1.28 Pain Relevance 0
A 4.7 fold down regulation of VIM expression and absence of vimentin immunoreactivity in the in situ tumor compared to normal mammary cells suggests both the tumor and the derived cell line have not undergone an epithelial-to-mesenchymal transition associated with increased invasive/migratory properties of epithelial cells [43,44].
Regulation (regulation) of Gene_expression (expression) of vimentin in epithelial cells associated with cancer
3) Confidence 0.13 Published 2008 Journal Mol Cancer Section Body Doc Link PMC2263075 Disease Relevance 0.80 Pain Relevance 0
Changes in anti-mutated citrullinated vimentin titres during infliximab therapy
Regulation (Changes) of Gene_expression (titres) of vimentin associated with infliximab
4) Confidence 0.08 Published 2008 Journal Arthritis Res Ther Section Body Doc Link PMC2656247 Disease Relevance 1.04 Pain Relevance 0.52

General Comments

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