INT211743

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Context Info
Confidence 0.09
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.10
Pain Relevance 1.25

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Pag1) intracellular (Pag1)
Anatomy Link Frequency
neurons 2
Pag1 (Mus musculus)
Mors1 (Mus musculus)
Pain Link Frequency Relevance Heat
opioid receptor 108 100.00 Very High Very High Very High
Morphine 91 99.44 Very High Very High Very High
Potency 2 90.36 High High
Analgesic 18 90.04 High High
Antinociceptive 11 79.96 Quite High
tolerance 43 71.88 Quite High
Opioid 42 63.32 Quite High
Immobilon 2 51.60 Quite High
antagonist 3 18.84 Low Low
agonist 21 15.52 Low Low
Disease Link Frequency Relevance Heat
Urological Neuroanatomy 12 100.00 Very High Very High Very High
Drug Dependence 3 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
Nociception 2 5.00 Very Low Very Low Very Low
Inflammatory Pain 2 5.00 Very Low Very Low Very Low
Decapitation 1 5.00 Very Low Very Low Very Low
Body Weight 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In contrast to morphine, the initial dose of DAMGO stimulated strong Ser375 phosphorylation and internalization of MORs in PAG neurons.
Positive_regulation (stimulated) of PAG Binding (internalization) of MORs in neurons associated with urological neuroanatomy, opioid receptor and morphine
1) Confidence 0.09 Published 2007 Journal Mol Pain Section Body Doc Link PMC1947952 Disease Relevance 0.10 Pain Relevance 1.25

General Comments

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