INT21182

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Context Info
Confidence 0.41
First Reported 1990
Last Reported 1990
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.08
Pain Relevance 0.43

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lyase activity (Pck1) nucleolus (Pck1) nucleus (Pck1)
lipid metabolic process (Pck1) cytoplasm (Pck1)
Pck1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Clonidine 3 94.76 High High
agonist 4 76.64 Quite High
Central nervous system 1 59.80 Quite High
Disease Link Frequency Relevance Heat
Bordatella Infection 1 78.36 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
On the other hand, treatment with Boc-Cys(Npys) inhibited the effect of several GTP analogs (GTP gamma S, guanylyl-imidodiphosphate, guanylyl)-(beta, gamma-methylene)-diphosphate, and GTP) on [3H]8-OH-DPAT and [3H]clonidine binding.
Negative_regulation (inhibited) of Regulation (effect) of GTP associated with clonidine
1) Confidence 0.41 Published 1990 Journal Mol. Pharmacol. Section Abstract Doc Link 2166901 Disease Relevance 0.08 Pain Relevance 0.43

General Comments

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