INT211827

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Context Info
Confidence 0.61
First Reported 2006
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 1.33
Pain Relevance 0.13

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (PVR) extracellular region (PVR) nucleolus (PVR)
plasma membrane (PVR) nucleus (PVR) cytoplasm (PVR)
PVR (Homo sapiens)
Pain Link Frequency Relevance Heat
nud 1 67.40 Quite High
headache 5 66.24 Quite High
Potency 1 51.28 Quite High
antagonist 1 12.16 Low Low
Central nervous system 34 5.00 Very Low Very Low Very Low
Spinal cord 12 5.00 Very Low Very Low Very Low
cva 9 5.00 Very Low Very Low Very Low
tolerance 4 5.00 Very Low Very Low Very Low
Inflammation 3 5.00 Very Low Very Low Very Low
Sciatic nerve 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 25 97.72 Very High Very High Very High
Syndrome 8 97.40 Very High Very High Very High
Increased Venous Pressure Under Development 11 95.40 Very High Very High Very High
Pulmonary Hypertension 82 83.92 Quite High
Nonarteritic Anterior Ischaemic Optic Neuropathy 1 79.76 Quite High
Arteritic Anterior Ischaemic Optic Neuropathy 1 79.48 Quite High
Polio 112 79.04 Quite High
Sprains And Strains 38 75.36 Quite High
Dyspepsia 1 67.40 Quite High
Headache 5 66.24 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Release of the virus RNA into the cell cytoplasm (uncoating) is thought to occur by destabilization of the virus capsid secondary to CD155-mediated release of the myristoylated capsid protein VP4 and of the putative N-terminal amphipathic helix of VP1 from deep within the virion [reviewed in [84]].
Localization (release) of CD155
1) Confidence 0.61 Published 2007 Journal Virol J Section Body Doc Link PMC1947962 Disease Relevance 0 Pain Relevance 0
Could C-cluster coxsackie A viruses evolve to utilize CD155 as a cellular receptor, thereby completely altering the disease syndromes with which they would be associated?
Localization (utilize) of CD155 associated with syndrome and disease
2) Confidence 0.57 Published 2007 Journal Virol J Section Body Doc Link PMC1947962 Disease Relevance 0.55 Pain Relevance 0
Acute administration of a single oral dose of sildenafil causes a significant decrease in mPAP and PVR with minimal or no affect on mean arterial pressure (MAP) and improvement, or a trend towards improvement, in cardiac output.
Localization (decrease) of PVR
3) Confidence 0.39 Published 2006 Journal Vascular Health and Risk Management Section Body Doc Link PMC1994020 Disease Relevance 0.78 Pain Relevance 0.13

General Comments

This test has worked.

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