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Context Info
Confidence 0.07
First Reported 2007
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 2.25
Pain Relevance 0.48

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

chromosome segregation (RIOK3) kinase activity (RIOK3)
RIOK3 (Homo sapiens)
Pain Link Frequency Relevance Heat
alcohol 5 98.88 Very High Very High Very High
addiction 30 98.20 Very High Very High Very High
cannabis 5 80.76 Quite High
Nicotine 1 79.76 Quite High
cocaine 2 75.84 Quite High
Opioid 1 74.64 Quite High
drug abuse 5 58.48 Quite High
opiate 9 50.00 Quite Low
tolerance 3 23.20 Low Low
Buprenorphine 4 6.76 Low Low
Disease Link Frequency Relevance Heat
Drug Dependence 54 100.00 Very High Very High Very High
Attention Deficit Hyperactivity Disorder 155 97.94 Very High Very High Very High
Conduct Disorder 6 82.68 Quite High
Cannabis Dependence 1 81.00 Quite High
Nicotine Addiction 1 80.20 Quite High
Adverse Drug Reaction 3 50.00 Quite Low
Opiate Addiction 1 50.00 Quite Low
Appetite Loss 4 45.64 Quite Low
Endometriosis (extended) 1 41.68 Quite Low
Acquired Immune Deficiency Syndrome Or Hiv Infection 1 27.04 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Endothelial progenitor cells (EPC's) were lower in the SUD (0.09+0.14 Vs. 0.26+0.20 cells/mcl, Student's T = 2.25, df = 19, P = 0.0367) both by absolute counts, and when numbers with EPC counts less than 0.15 × 1011 were considered (Fisher Exact Test = 0.0299, Yates corrected Chi Squared 0.047, df = 1, O.R. = 0.09, C.I. 0.01–0.97) notwithstanding the significantly older age of the N-SUD group.
Negative_regulation (lower) of SUD associated with drug dependence
1) Confidence 0.07 Published 2007 Journal Subst Abuse Treat Prev Policy Section Body Doc Link PMC1949819 Disease Relevance 0.24 Pain Relevance 0
Probands with ADHD who did not differ from those without ADHD in absolute rates of SUD, still had an earlier onset, a longer duration, and higher rates of severely impairing SUD as well as higher rates of alcohol and drug dependence than non-ADHD children [23].
Negative_regulation (impairing) of SUD associated with drug dependence, addiction, attention deficit hyperactivity disorder and alcohol
2) Confidence 0.01 Published 2010 Journal Eur Child Adolesc Psychiatry Section Body Doc Link PMC3012210 Disease Relevance 2.02 Pain Relevance 0.48

General Comments

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