INT211939

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Context Info
Confidence 0.33
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.35
Pain Relevance 0.06

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (Sox9) signal transduction (Sox9) nucleus (Sox9)
extracellular matrix organization (Sox9) protein complex assembly (Sox9) DNA binding (Sox9)
Sox9 (Mus musculus)
Pain Link Frequency Relevance Heat
antagonist 6 71.84 Quite High
Kinase C 2 52.68 Quite High
anesthesia 2 5.00 Very Low Very Low Very Low
depression 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Targeted Disruption 8 97.48 Very High Very High Very High
Osteoporosis 68 81.20 Quite High
Fracture Healing 72 62.44 Quite High
Tibia Fractures 6 55.56 Quite High
Injury 12 5.00 Very Low Very Low Very Low
Calcification 2 5.00 Very Low Very Low Very Low
Bone Fracture 2 5.00 Very Low Very Low Very Low
Familial Adenomatous Polyposis 2 5.00 Very Low Very Low Very Low
Repression 2 5.00 Very Low Very Low Very Low
Frailty 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
SOX9 was also down-regulated after treatment of Ad-DKK1, suggesting an inhibition of chondrogenic differentiation after blocking of WNT/?
Regulation (regulated) of SOX9
1) Confidence 0.33 Published 2007 Journal PLoS Medicine Section Body Doc Link PMC1950214 Disease Relevance 0.06 Pain Relevance 0.06
We also observed a significant down-regulation of SOX9 and RUNX2 in both of these mice (Figure 2L and 2M).
Regulation (regulation) of SOX9
2) Confidence 0.33 Published 2007 Journal PLoS Medicine Section Body Doc Link PMC1950214 Disease Relevance 0.29 Pain Relevance 0

General Comments

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