INT211948

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Context Info
Confidence 0.33
First Reported 2006
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.94
Pain Relevance 0.08

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (Sox9) signal transduction (Sox9) nucleus (Sox9)
extracellular matrix organization (Sox9) protein complex assembly (Sox9) DNA binding (Sox9)
Sox9 (Mus musculus)
Pain Link Frequency Relevance Heat
Osteoarthritis 15 83.96 Quite High
cytokine 3 5.00 Very Low Very Low Very Low
depression 3 5.00 Very Low Very Low Very Low
antagonist 3 5.00 Very Low Very Low Very Low
Inflammation 2 5.00 Very Low Very Low Very Low
adenocard 2 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
spinal inflammation 1 5.00 Very Low Very Low Very Low
Kinase C 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Aging 13 84.36 Quite High
Osteoarthritis 15 83.96 Quite High
Calcification 47 83.72 Quite High
Metabolic Disorder 1 80.28 Quite High
Fracture Healing 36 77.36 Quite High
Osteoporosis 38 77.28 Quite High
Chondrocalcinosis 3 74.32 Quite High
Repression 1 70.60 Quite High
Disease 9 39.68 Quite Low
Injury 6 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
However, SOX9 was down-regulated in ?
Regulation (regulated) of Gene_expression (was) of SOX9
1) Confidence 0.33 Published 2007 Journal PLoS Medicine Section Body Doc Link PMC1950214 Disease Relevance 0.41 Pain Relevance 0
PPi appears to directly regulate expression of certain genes (including inductive effects first described by us for osteopontin and MMP-13 expression and suppressive effects on Sox9 expression)[18, 33–35].
Regulation (effects) of Gene_expression (expression) of Sox9
2) Confidence 0.29 Published 2006 Journal Purinergic Signal Section Body Doc Link PMC2254483 Disease Relevance 0.53 Pain Relevance 0.08

General Comments

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