INT212012

Context Info Confidence 0.04 First Reported 2007 Last Reported 2007 Negated 0 Speculated 1 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.59 Pain Relevance 0

signal transduction (GNRH1) extracellular space (GNRH1) extracellular region (GNRH1) nucleus (RAD51D) DNA binding (RAD51D) cell-cell signaling (GNRH1)

RAD51D (Homo sapiens) GNRH1 (Homo sapiens)

Pain Link Frequency Relevance Heat agonist 1 5.00 depression 1 5.00 headache 1 5.00 nud 1 5.00

Disease Link Frequency Relevance Heat Galactorrhea 37 97.44 Hemorrhage 1 45.72 Reprotox - General 1 4 44.44 Syndrome 1 42.40 Prolactinoma 3 26.56 Thyroid Disease 1 25.20 Hypercalcemia 5 5.12 Fatigue 2 5.00 Sleep Disorders 1 5.00 Osteoporosis 1 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

In a previous study in which r-hPRL was administered every 12 hours for seven days to examine its effect on GnRH secretion [27], four of six participants developed expressible galactorrhea, however, this study was not powered to examine efficacy.

r-hPRL Spec (examine) Regulation (effect) of GnRH associated with galactorrhea

1) Confidence 0.04 Published 2007 Journal Int Breastfeed J Section Body Doc Link PMC1950489 Disease Relevance 0.59 Pain Relevance 0

General Comments

This test has worked.