INT212022

Context Info Confidence 0.27 First Reported 2007 Last Reported 2008 Negated 0 Speculated 0 Reported most in Body Documents 4 Total Number 4 Disease Relevance 0.81 Pain Relevance 0

nucleus (RAD51D) DNA binding (RAD51D)

RAD51D (Homo sapiens)

Pain Link Frequency Relevance Heat nud 3 43.28 agonist 3 5.00 depression 3 5.00 headache 3 5.00 IPN 1 5.00

Disease Link Frequency Relevance Heat Galactorrhea 111 97.02 Hypercalcemia 15 84.00 Prolactinoma 9 65.44 Dyspepsia 3 43.28 Thyroid Disease 3 34.12 Syndrome 3 25.28 Reprotox - General 1 12 5.00 Fatigue 6 5.00 Sleep Disorders 3 5.00 Osteoporosis 3 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

As in yeast, rad51 paralogs (rad51b, rad51d, xrcc2 and xrcc3) that participate in HR in vertebrates were not found in E. histolytica (Table 1).

Gene_expression (paralogs) of rad51d

1) Confidence 0.27 Published 2008 Journal BMC Mol Biol Section Body Doc Link PMC2324109 Disease Relevance 0 Pain Relevance 0

g/kg r-hPRL injection (Figure 1).

Gene_expression (injection) of r-hPRL

2) Confidence 0.07 Published 2007 Journal Int Breastfeed J Section Body Doc Link PMC1950489 Disease Relevance 0.18 Pain Relevance 0

Of note, short-term hyperprolactinemia did not disrupt the normal estradiol increase across the follicular phase of the menstrual cycle in our current or previous study using twice daily r-hPRL dosing, nor did a 12 hour r-hPRL infusion cause fluctuations in estradiol concentration [27].

Gene_expression (dosing) of r-hPRL associated with galactorrhea

3) Confidence 0.07 Published 2007 Journal Int Breastfeed J Section Body Doc Link PMC1950489 Disease Relevance 0.46 Pain Relevance 0

The prolactin level was unchanged at baseline before the seventh r-hPRL injection (16.9 ± 1.5 ?

Gene_expression (injection) of r-hPRL

4) Confidence 0.07 Published 2007 Journal Int Breastfeed J Section Body Doc Link PMC1950489 Disease Relevance 0.18 Pain Relevance 0

General Comments

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