INT212025

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Context Info
Confidence 0.08
First Reported 2007
Last Reported 2007
Negated 1
Speculated 1
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.29
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (RAD51D) DNA binding (RAD51D)
RAD51D (Homo sapiens)
Pain Link Frequency Relevance Heat
agonist 2 5.00 Very Low Very Low Very Low
depression 2 5.00 Very Low Very Low Very Low
headache 2 5.00 Very Low Very Low Very Low
nud 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hypercalcemia 10 100.00 Very High Very High Very High
Galactorrhea 74 97.84 Very High Very High Very High
Thyroid Disease 2 91.92 High High
Prolactinoma 6 91.20 High High
Syndrome 2 83.08 Quite High
Hemorrhage 2 45.72 Quite Low
Reprotox - General 1 8 44.44 Quite Low
Fatigue 4 5.00 Very Low Very Low Very Low
Sleep Disorders 2 5.00 Very Low Very Low Very Low
Osteoporosis 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
It is encouraging that r-hPRL did not increase markers of bone resorption or decrease bone specific alkaline phosphatase, a marker of bone formation, during short-term use for its potential development as a galactagogue.
Neg (not) Localization (decrease) of r-hPRL associated with hypercalcemia
1) Confidence 0.08 Published 2007 Journal Int Breastfeed J Section Body Doc Link PMC1950489 Disease Relevance 0.70 Pain Relevance 0
In a previous study in which r-hPRL was administered every 12 hours for seven days to examine its effect on GnRH secretion [27], four of six participants developed expressible galactorrhea, however, this study was not powered to examine efficacy.
Spec (examine) Localization (secretion) of r-hPRL associated with galactorrhea
2) Confidence 0.08 Published 2007 Journal Int Breastfeed J Section Body Doc Link PMC1950489 Disease Relevance 0.59 Pain Relevance 0

General Comments

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