INT212128

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Context Info
Confidence 0.11
First Reported 2007
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 5
Total Number 5
Disease Relevance 0.92
Pain Relevance 0.75

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
plasma cell 1
CLC 1
Cl (Mus musculus)
Pain Link Frequency Relevance Heat
gABA 129 99.06 Very High Very High Very High
GABAergic 13 96.96 Very High Very High Very High
Central nervous system 19 96.56 Very High Very High Very High
addiction 5 76.92 Quite High
Dopamine 78 50.00 Quite Low
tetrodotoxin 9 21.12 Low Low
antagonist 28 5.00 Very Low Very Low Very Low
agonist 28 5.00 Very Low Very Low Very Low
Neurotransmitter 25 5.00 Very Low Very Low Very Low
Glutamate 18 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Apoptosis 177 98.36 Very High Very High Very High
Targeted Disruption 18 92.32 High High
Disease 20 81.36 Quite High
Pressure And Volume Under Development 17 66.08 Quite High
Ocular Toxicity (including Many Sub-types) 1 63.20 Quite High
Death 43 55.40 Quite High
Vitelliform Macular Dystrophy 1 52.84 Quite High
Generalized Epilepsy 6 51.84 Quite High
Blindness 8 50.00 Quite Low
Retina Disease 8 35.92 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The finding that GABA acts on the retinal PER2::LUC rhythms through ionotropic, Cl?
Cl Binding (ionotropic) of associated with gaba
1) Confidence 0.11 Published 2008 Journal PLoS Biology Section Body Doc Link PMC2567003 Disease Relevance 0 Pain Relevance 0.58
This challenge is based largely on several observations, the most compelling of which is that Cl?
Cl Binding (observations) of
2) Confidence 0.06 Published 2008 Journal The Journal of General Physiology Section Body Doc Link PMC2571971 Disease Relevance 0.29 Pain Relevance 0
Association of the AE3 Cl?
Cl Binding (Association) of
3) Confidence 0.05 Published 2007 Journal PLoS ONE Section Body Doc Link PMC1950688 Disease Relevance 0.10 Pain Relevance 0
exchange across the plasma cell membrane, regulating [Cl?]
Cl Binding (across) of in plasma cell
4) Confidence 0.05 Published 2007 Journal PLoS ONE Section Body Doc Link PMC1950688 Disease Relevance 0 Pain Relevance 0.13
The CLC channel family, a group of voltage-dependent Cl?
Cl Binding (group) of in CLC
5) Confidence 0.03 Published 2008 Journal Current Neuropharmacology Section Body Doc Link PMC2647147 Disease Relevance 0.53 Pain Relevance 0.04

General Comments

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