INT212172

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Context Info
Confidence 0.36
First Reported 2007
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 7
Total Number 7
Disease Relevance 1.38
Pain Relevance 0.09

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Adrm1) nucleus (Adrm1) cytoplasm (Adrm1)
Anatomy Link Frequency
arm 4
shoulder 1
neck 1
Adrm1 (Mus musculus)
Pain Link Frequency Relevance Heat
Crohn's disease 1 97.48 Very High Very High Very High
Glutamate receptor 8 89.92 High High
Pain 12 25.84 Quite Low
Action potential 54 5.00 Very Low Very Low Very Low
addiction 10 5.00 Very Low Very Low Very Low
action potential duration 10 5.00 Very Low Very Low Very Low
Eae 6 5.00 Very Low Very Low Very Low
tetrodotoxin 5 5.00 Very Low Very Low Very Low
Nav1.1 4 5.00 Very Low Very Low Very Low
shoulder pain 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Gastrointestinal Disease 3 98.68 Very High Very High Very High
Disease 9 97.16 Very High Very High Very High
Irritable Bowel Syndrome /

Irritable Bowel Syndrome Super

1 96.68 Very High Very High Very High
Cramps 3 91.68 High High
Obesity 2 91.60 High High
Myalgia 3 89.68 High High
Arrhythmogenic Right Ventricular Dysplasia 26 84.28 Quite High
Body Weight 6 74.76 Quite High
Syndrome 8 57.24 Quite High
Targeted Disruption 14 50.00 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In mammals, USP14 and Rpn13/UCH37, both deubiquitylating enzymes or DUBs, influence substrate degradation through their interaction with the 26S proteasome (Koulich et al., 2008).
Rpn13 Binding (interaction) of
1) Confidence 0.36 Published 2010 Journal Frontiers in Molecular Neuroscience Section Body Doc Link PMC2901091 Disease Relevance 0 Pain Relevance 0.04
Complaints of arm, neck and shoulder (CANS) were recognized in the early seventies as an important cause of work disability.
arm Binding (recognized) of in shoulder
2) Confidence 0.13 Published 2007 Journal BMC Musculoskelet Disord Section Body Doc Link PMC1952062 Disease Relevance 0.18 Pain Relevance 0
Complaints of arm, neck and shoulder (CANS) were recognized in the early seventies as an important cause of work disability.
arm Binding (recognized) of in neck
3) Confidence 0.04 Published 2007 Journal BMC Musculoskelet Disord Section Body Doc Link PMC1952062 Disease Relevance 0.18 Pain Relevance 0
Complaints of arm, neck and shoulder (CANS) were recognized in the early seventies as an important cause of work disability.
arm Binding (recognized) of in arm
4) Confidence 0.04 Published 2007 Journal BMC Musculoskelet Disord Section Body Doc Link PMC1952062 Disease Relevance 0.18 Pain Relevance 0
arm spanning 4.1 kb of the Scn3b locus commencing just upstream of the third coding exon splice donor (3?
arm Binding (commencing) of in arm
5) Confidence 0.03 Published 2008 Journal Prog Biophys Mol Biol Section Body Doc Link PMC2764399 Disease Relevance 0.14 Pain Relevance 0
arm spanning 2.0 kb of the Scn3b locus terminating downstream of the third coding exon splice acceptor (5?
arm Binding (terminating) of in arm
6) Confidence 0.03 Published 2008 Journal Prog Biophys Mol Biol Section Body Doc Link PMC2764399 Disease Relevance 0.22 Pain Relevance 0
Interestingly, the long arm of chromosome 5 (5q) is a region associated with the risk of developing the gastrointestinal disorders of Crohn's disease and IBS (Genetics Home Reference, http://ghr.nlm.nih.gov/). miR-103 has also been shown to stimulate adipogenesis that accelerates fat cell proliferation, and is down-regulated in obesity [32].
arm Binding (associated) of in arm associated with gastrointestinal disease, crohn's disease, obesity and disease
7) Confidence 0.01 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2944884 Disease Relevance 0.38 Pain Relevance 0.05

General Comments

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