INT212176

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Context Info
Confidence 0.75
First Reported 2007
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 7
Total Number 7
Disease Relevance 6.05
Pain Relevance 0.24

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (CEACAM5)
Anatomy Link Frequency
arm 1
CEACAM5 (Homo sapiens)
Pain Link Frequency Relevance Heat
imagery 25 99.52 Very High Very High Very High
positron emission tomography 1 86.80 High High
palliative 5 70.68 Quite High
Inflammation 9 41.08 Quite Low
tolerance 1 18.12 Low Low
backache 2 9.80 Low Low
abdominal pain 3 9.36 Low Low
alcohol 2 5.00 Very Low Very Low Very Low
antagonist 2 5.00 Very Low Very Low Very Low
Central nervous system 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Adhesions 2 100.00 Very High Very High Very High
Cancer 203 99.64 Very High Very High Very High
Merkel Cell Carcinoma 4 99.52 Very High Very High Very High
Dermoids 52 98.80 Very High Very High Very High
Adenocarcinoma 23 95.92 Very High Very High Very High
Metastasis 38 94.44 High High
Diabetes Mellitus 2 93.48 High High
Cyst 22 91.44 High High
Lung Cancer 1 91.32 High High
Recurrence 81 87.40 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
CDX2 and mCEA are rarely expressed in CRSmCC and hence they may be of value in differentiating it from poorly differentiated colorectal adenocarcinoma.
Gene_expression (expressed) of CEA associated with adenocarcinoma
1) Confidence 0.75 Published 2007 Journal Diagn Pathol Section Body Doc Link PMC2034542 Disease Relevance 1.11 Pain Relevance 0
At each visit, we took a medical history, measured serum CEA levels, and performed a physical examination (including rectal examination).
Gene_expression (levels) of CEA
2) Confidence 0.65 Published 2009 Journal Yonsei Medical Journal Section Body Doc Link PMC2768247 Disease Relevance 0.67 Pain Relevance 0.04
Mean CEA and CA 19-9 levels were also similar in each arm

Treatment delivery

Gene_expression (levels) of CEA in arm
3) Confidence 0.65 Published 2010 Journal Gut Section Body Doc Link PMC2981019 Disease Relevance 0.15 Pain Relevance 0.07
The traditional serum markers, such as CEA and CA19-9, would be expected to be significantly lower in dermoid cysts rather than in other pancreatic cystic neoplasms; however, our experience does not confirm this prediction [25].
Gene_expression (expected) of CEA associated with dermoids and cancer
4) Confidence 0.56 Published 2007 Journal World J Surg Oncol Section Body Doc Link PMC1952065 Disease Relevance 1.80 Pain Relevance 0
Laboratory studies showed normal values except for increase of CA 19-9 levels (CEA, and Ca 19-9 were tested).
Gene_expression (tested) of CEA
5) Confidence 0.49 Published 2007 Journal World J Surg Oncol Section Body Doc Link PMC1952065 Disease Relevance 0.70 Pain Relevance 0.13
MammoStrat® uses conventional paraffin-embedded tissue to assay five markers by IHC: tumor protein p53 (TP53) — known to play a central role in cell cycle regulation; Hpa II tiny fragments locus 9C (HTF9C) — involved in DNA replication and cell cycle control; carcinoembryonic antigen-related cell adhesion molecule 5 (CEACAM5) — aberrantly expressed in some cancers; nmyc downstream-regulated gene 1 (NDRG1) — may function as a signaling protein in growth arrest and cellular differentiation; and solute carrier family 7 (cationic amino acid transporter, y+ system), member 5 (SLC7A5) — mediates amino acid transport.
Gene_expression (expressed) of adhesion molecule 5 associated with cancer and adhesions
6) Confidence 0.35 Published 2010 Journal Current Genomics Section Body Doc Link PMC2878980 Disease Relevance 0.82 Pain Relevance 0
MammoStrat® uses conventional paraffin-embedded tissue to assay five markers by IHC: tumor protein p53 (TP53) — known to play a central role in cell cycle regulation; Hpa II tiny fragments locus 9C (HTF9C) — involved in DNA replication and cell cycle control; carcinoembryonic antigen-related cell adhesion molecule 5 (CEACAM5) — aberrantly expressed in some cancers; nmyc downstream-regulated gene 1 (NDRG1) — may function as a signaling protein in growth arrest and cellular differentiation; and solute carrier family 7 (cationic amino acid transporter, y+ system), member 5 (SLC7A5) — mediates amino acid transport.
Gene_expression (expressed) of CEACAM5 associated with cancer and adhesions
7) Confidence 0.35 Published 2010 Journal Current Genomics Section Body Doc Link PMC2878980 Disease Relevance 0.81 Pain Relevance 0

General Comments

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