INT212185

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Context Info
Confidence 0.33
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 5
Disease Relevance 0.67
Pain Relevance 0.52

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (Sned1) cellular_component (Sned1) biological_process (Sned1)
Anatomy Link Frequency
brain 4
Sned1 (Mus musculus)
Pain Link Frequency Relevance Heat
Hippocampus 95 93.12 High High
Spinal cord 10 5.00 Very Low Very Low Very Low
Inflammation 10 5.00 Very Low Very Low Very Low
ketamine 5 5.00 Very Low Very Low Very Low
Nerve growth factor 5 5.00 Very Low Very Low Very Low
ischemia 5 5.00 Very Low Very Low Very Low
Enkephalin 5 5.00 Very Low Very Low Very Low
Inflammatory response 5 5.00 Very Low Very Low Very Low
Neurotransmitter 5 5.00 Very Low Very Low Very Low
alcohol 5 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Alzheimer's Dementia 200 84.56 Quite High
Infection 10 64.72 Quite High
Targeted Disruption 75 56.80 Quite High
Amyloid Plaque 30 50.00 Quite Low
Toxicity 5 19.52 Low Low
Disease 45 18.20 Low Low
Cancer 15 16.68 Low Low
Gliosis 30 5.00 Very Low Very Low Very Low
Death 10 5.00 Very Low Very Low Very Low
Encephalitis 10 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
clearance from the brain due to sNEP delivery, we stained sagittal sections for A?
Positive_regulation (due) of Gene_expression (delivery) of sNEP in brain
1) Confidence 0.33 Published 2007 Journal PLoS Medicine Section Body Doc Link PMC1952204 Disease Relevance 0.11 Pain Relevance 0.26
Both wild-type NEP and sNEP were capable of promoting A?
Positive_regulation (promoting) of Gene_expression (capable) of sNEP
2) Confidence 0.33 Published 2007 Journal PLoS Medicine Section Body Doc Link PMC1952204 Disease Relevance 0 Pain Relevance 0
degradation assays, conditioned medium from APP-overexpressing CHO cells was combined with 10-fold concentrated conditioned medium from CHO cells overexpressing empty vector, NEP, or sNEP and incubated at 37 °C for 18 h.
Positive_regulation (overexpressing) of Gene_expression (overexpressing) of sNEP
3) Confidence 0.33 Published 2007 Journal PLoS Medicine Section Body Doc Link PMC1952204 Disease Relevance 0.22 Pain Relevance 0
degradation assays, conditioned medium from APP-overexpressing CHO cells was combined with 10-fold concentrated conditioned medium from CHO cells overexpressing empty vector, NEP, or sNEP and incubated at 37 °C for 18 h.
Positive_regulation (overexpressing) of Gene_expression (overexpressing) of sNEP
4) Confidence 0.33 Published 2007 Journal PLoS Medicine Section Body Doc Link PMC1952204 Disease Relevance 0.23 Pain Relevance 0
clearance from the brain due to sNEP delivery, we stained sagittal sections for A?
Positive_regulation (delivery) of Gene_expression (delivery) of sNEP in brain
5) Confidence 0.33 Published 2007 Journal PLoS Medicine Section Body Doc Link PMC1952204 Disease Relevance 0.11 Pain Relevance 0.26

General Comments

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