INT212251

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Context Info
Confidence 0.14
First Reported 2007
Last Reported 2007
Negated 1
Speculated 0
Reported most in Body
Documents 1
Total Number 4
Disease Relevance 0
Pain Relevance 0.41

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Mention Frequency
body 1
A10L (Vaccinia virus)
A10L - A10L (4) A10L - D14K (1)
Pain Term Frequency Confidence Heat
conotoxin 132 97.68 Very High Very High Very High
Potency 24 90.08 High High
antagonist 8 50.64 Quite High
Analgesic 4 5.00 Very Low Very Low Very Low
Neuropathic pain 4 5.00 Very Low Very Low Very Low
Nicotine 24 5.00 Very Low Very Low Very Low
addiction 4 5.00 Very Low Very Low Very Low
gABA 4 5.00 Very Low Very Low Very Low
agonist 16 5.00 Very Low Very Low Very Low
Disease Term Frequency Confidence Heat
Nicotine Addiction 4 5.00 Very Low Very Low Very Low
Disease 8 5.00 Very Low Very Low Very Low
Neuropathic Pain 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Inde</span>ed, substitution of Arg5 in PnIA(A10L) produced a gain-of-function analog with similar properties to TxIA.
Gene_expression (produced) of A10L (A10L)
1) Confidence 0.14 Published 2007 Journal EMBO J Section Body Doc Link PMC1952216 Disease Relevance 0 Pain Relevance 0.17
The structure of TxIA(A10L) itself is very similar to other ?
Gene_expression (structure) of A10L (A10L)
2) Confidence 0.14 Published 2007 Journal EMBO J Section Body Doc Link PMC1952216 Disease Relevance 0 Pain Relevance 0.07
3° rigid body rotations of the monomers in the Ac-AChBP complex with PnIA(A10L D14K) (Celie et al, 2005a), whereas these rotations were not seen in the Ac-AChBP complex with ImI (Ulens et al, 2006).
Neg (not) Gene_expression (seen) of A10L D14K (A10L, D14K) in body
3) Confidence 0.13 Published 2007 Journal EMBO J Section Body Doc Link PMC1952216 Disease Relevance 0 Pain Relevance 0.08
The structure of Ac-AChBP in complex with TxIA(A10L) is very similar to other ?
Gene_expression (structure) of A10L (A10L)
4) Confidence 0.13 Published 2007 Journal EMBO J Section Body Doc Link PMC1952216 Disease Relevance 0 Pain Relevance 0.07

General Comments

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