INT212388

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Context Info
Confidence 0.40
First Reported 2007
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 4
Disease Relevance 0.30
Pain Relevance 0.25

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (Zic1) nucleus (Zic1) intracellular (Zic1)
DNA binding (Zic1) cytoplasm (Zic1)
Anatomy Link Frequency
interneurons 2
Zic1 (Mus musculus)
Pain Link Frequency Relevance Heat
substantia gelatinosa 6 98.40 Very High Very High Very High
Pain 3 68.32 Quite High
Spinal cord 6 52.60 Quite High
imagery 1 28.44 Quite Low
tetrodotoxin 15 5.00 Very Low Very Low Very Low
Central nervous system 4 5.00 Very Low Very Low Very Low
Thalamus 4 5.00 Very Low Very Low Very Low
Dorsal horn neuron 3 5.00 Very Low Very Low Very Low
sodium channel 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Adhesions 4 90.72 High High
Pain 3 68.32 Quite High
Targeted Disruption 66 30.76 Quite Low
Apoptosis 6 5.00 Very Low Very Low Very Low
Acquired Immune Deficiency Syndrome Or Hiv Infection 3 5.00 Very Low Very Low Very Low
Congenital Anomalies 2 5.00 Very Low Very Low Very Low
Sprains And Strains 1 5.00 Very Low Very Low Very Low
Hypopigmentation 1 5.00 Very Low Very Low Very Low
Overdose 1 5.00 Very Low Very Low Very Low
Embryonic Lethality 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Although binding partners for Ten_m3 have not yet been identified, interactions with zic genes or other molecules expressed in ipsilateral axons, such as EphB1, are possible.
Gene_expression (expressed) of zic
1) Confidence 0.40 Published 2007 Journal PLoS Biol Section Body Doc Link PMC1964777 Disease Relevance 0.17 Pain Relevance 0
The expression patterns of Prxxl1 (DRG11), Lbxcor1(Corl1), Zic1-5, Tsh2, Sall3, Zfhx1b, Bcl11a indicate that these SSTFs are expressed in association interneurons [9], [36]–[38].
Gene_expression (expression) of Zic1-5 in interneurons
2) Confidence 0.07 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2527684 Disease Relevance 0.06 Pain Relevance 0.11
The expression patterns of Prxxl1 (DRG11), Lbxcor1(Corl1), Zic1-5, Tsh2, Sall3, Zfhx1b, Bcl11a indicate that these SSTFs are expressed in association interneurons [9], [36]–[38].
Gene_expression (expressed) of Zic1-5 in interneurons
3) Confidence 0.07 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2527684 Disease Relevance 0.07 Pain Relevance 0.12
e6, Mafa1, Pknox2, Sall3, Tshz2, Lbxcor1, Gbx2, Satb2, Sal4, and Zic1-5), repressed targets (Isl1, Foxd3, Olig3, Otp, FoxP2, Hmx2, Hmx3, Nr4a2(Nurr1), Sall1), and neutral genes (Sall2, Uncx4.1, Bcl11b) were designed according to the online resource PRIMER BANK.
Gene_expression (designed) of Zic1-5
4) Confidence 0.07 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2527684 Disease Relevance 0 Pain Relevance 0.03

General Comments

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