INT212392

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Context Info
Confidence 0.03
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 0.20
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell adhesion (Epha1) plasma membrane (Epha1) kinase activity (Epha1)
Anatomy Link Frequency
eye 1
patterning 1
Epha1 (Mus musculus)
Pain Link Frequency Relevance Heat
Central nervous system 3 49.60 Quite Low
tetrodotoxin 45 5.00 Very Low Very Low Very Low
Thalamus 12 5.00 Very Low Very Low Very Low
sodium channel 3 5.00 Very Low Very Low Very Low
imagery 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Ganglion Cysts 3 83.76 Quite High
Hypopigmentation 3 58.40 Quite High
Adhesions 12 54.44 Quite High
Targeted Disruption 144 5.00 Very Low Very Low Very Low
Congenital Anomalies 6 5.00 Very Low Very Low Very Low
Sprains And Strains 3 5.00 Very Low Very Low Very Low
Overdose 3 5.00 Very Low Very Low Very Low
Embryonic Lethality 3 5.00 Very Low Very Low Very Low
Vibrio Infection 3 5.00 Very Low Very Low Very Low
Strabismus 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Because repulsive EphA–ephrinA interactions are reported to confine ipsilateral axons to dorsomedial dLGN [13], the ventrolateral expansion of the ipsilateral terminal region is suggestive of changes in EphA–ephrinA expression.
EphA Binding (interactions) of
1) Confidence 0.03 Published 2007 Journal PLoS Biol Section Body Doc Link PMC1964777 Disease Relevance 0.05 Pain Relevance 0
However, EphA–ephrinA interactions also play a major role in the establishment of topography of contralateral visual projections to central targets [14–18], which complicates the interpretation that these molecules have a role in eye-specific patterning.
EphA Binding (interactions) of in patterning
2) Confidence 0.03 Published 2007 Journal PLoS Biol Section Body Doc Link PMC1964777 Disease Relevance 0.14 Pain Relevance 0
However, as the targeting of contralateral axons is not appreciably altered, and this is known to be affected by EphA–ephrinA interactions [14,18], it is possible that other or additional mechanisms are involved in targeting of eye-specific projections.
EphA Binding (interactions) of in eye
3) Confidence 0.02 Published 2007 Journal PLoS Biol Section Body Doc Link PMC1964777 Disease Relevance 0 Pain Relevance 0

General Comments

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