INT212413

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Context Info
Confidence 0.00
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (PRKAB1) signal transduction (PRKAB1) transport (SLC12A1)
nucleus (PRKAB1) plasma membrane (SLC12A1) transmembrane transport (SLC12A1)
SLC12A1 (Homo sapiens)
PRKAB1 (Homo sapiens)
SLC12A1 - R225W (1)
Pain Link Frequency Relevance Heat
imagery 2 5.00 Very Low Very Low Very Low
lidocaine 1 5.00 Very Low Very Low Very Low
tolerance 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Targeted Disruption 3 42.96 Quite Low
Obesity 8 5.00 Very Low Very Low Very Low
Diabetes Mellitus 6 5.00 Very Low Very Low Very Low
Syndrome 4 5.00 Very Low Very Low Very Low
Coronary Heart Disease 2 5.00 Very Low Very Low Very Low
Insulin Resistance 2 5.00 Very Low Very Low Very Low
Disease 2 5.00 Very Low Very Low Very Low
Heart Arrhythmia 2 5.00 Very Low Very Low Very Low
Impaired Glucose Tolerance 1 5.00 Very Low Very Low Very Low
Hypertrophy 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We believe that the R225W variant is affecting AMPK activity without affecting the level of transcription or translation of the PRKAG3 gene.


variant (R225W) Regulation (affecting) of AMPK
1) Confidence 0.00 Published 2007 Journal PLoS ONE Section Body Doc Link PMC1964808 Disease Relevance 0 Pain Relevance 0

General Comments

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