INT212444

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Context Info
Confidence 0.18
First Reported 2007
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 4
Total Number 4
Disease Relevance 4.83
Pain Relevance 0.12

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

pigmentation (TYR) cell proliferation (TYR) lysosome (TYR)
cytoplasm (TYR)
Anatomy Link Frequency
Bands 2
TYR (Homo sapiens)
Pain Link Frequency Relevance Heat
bradykinin 75 99.98 Very High Very High Very High
alcohol 12 75.20 Quite High
Eae 3 64.00 Quite High
Inflammation 22 10.44 Low Low
fibrosis 6 5.00 Very Low Very Low Very Low
imagery 5 5.00 Very Low Very Low Very Low
Mechanotransduction 4 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
Dismenorea 2 5.00 Very Low Very Low Very Low
cerebral cortex 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hepatitis 66 100.00 Very High Very High Very High
Chronic Hepatitis 62 99.84 Very High Very High Very High
Cirrhosis 114 99.52 Very High Very High Very High
Disease 209 99.32 Very High Very High Very High
Down Syndrome 16 90.88 High High
Alcohol Addiction 6 75.20 Quite High
Infection 10 71.28 Quite High
Stress 104 69.92 Quite High
Adhesions 47 56.92 Quite High
Hepatitis C Virus Infection 14 36.88 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
A common element of this molecular profile appearing in all presenilin and non-presenilin-based genetic forms of AD risk we tested is the initial BK-induced BKB2R Tyr phosphorylation itself, positioned early in the BKB2R signaling cascade [8], [12], [13], [14].
Positive_regulation (induced) of Phosphorylation (phosphorylation) of Tyr associated with disease and bradykinin
1) Confidence 0.18 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2644820 Disease Relevance 0.86 Pain Relevance 0.08
Tyrosine (Tyr)-phosphorylated STAT3 was strongly reduced in AH and was increased in LDH.
Positive_regulation (increased) of Phosphorylation (phosphorylated) of Tyr associated with hepatitis
2) Confidence 0.11 Published 2007 Journal Comp Hepatol Section Body Doc Link PMC1971050 Disease Relevance 1.77 Pain Relevance 0
The phosphorylated form threonine/tyrosine (Thr/Tyr)-phosphorylated ERK1/2 was strongly increased in CH and LDH.
Positive_regulation (increased) of Phosphorylation (phosphorylated) of Tyr associated with chronic hepatitis
3) Confidence 0.11 Published 2007 Journal Comp Hepatol Section Body Doc Link PMC1971050 Disease Relevance 2.14 Pain Relevance 0.04
Bands at 250, 130 and 100 kDa that displayed a consistent increase in intensity (indicating either an increase in Tyr phosphorylation or a binding to such a protein in the immunoprecipitate) after stretch were subjected mass spectrometric analysis.
Positive_regulation (increase) of Phosphorylation (phosphorylation) of Tyr in Bands
4) Confidence 0.11 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2759504 Disease Relevance 0.06 Pain Relevance 0

General Comments

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