INT212527
From wiki-pain
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Sentences Mentioned In
Key: | Protein | Mutation | Event | Anatomy | Negation | Speculation | Pain term | Disease term |
Furthermore, the presence of PC inhibited binding of both SAP and CRP (used as a positive control, as CRP is known to bind to S. pneumoniae cell wall PC) to a similar degree, suggesting that PC is a major ligand for SAP binding to S. pneumoniae (Figure 1D and 1E). | |||||||||||||||
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The mechanisms by which the classical pathway is activated by S. pneumoniae infection include recognition of PC on the bacterial surface by natural IgM and CRP [34,3740], and binding of bacterial capsular polysaccharide to the lectin SIGN-R1 expressed on marginal zone macrophages within the spleen [41]. | |||||||||||||||
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