INT212553

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Context Info
Confidence 0.39
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.30
Pain Relevance 0.12

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (IGF1) extracellular space (IGF1) extracellular region (IGF1)
Anatomy Link Frequency
cartilage 2
IGF1 (Homo sapiens)
Pain Link Frequency Relevance Heat
metalloproteinase 10 93.28 High High
Inflammation 17 66.76 Quite High
Osteoarthritis 7 5.00 Very Low Very Low Very Low
cytokine 3 5.00 Very Low Very Low Very Low
COX2 2 5.00 Very Low Very Low Very Low
Analgesic 2 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
qutenza 2 5.00 Very Low Very Low Very Low
agonist 2 5.00 Very Low Very Low Very Low
analgesia 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Toxicity 15 87.36 High High
INFLAMMATION 16 66.76 Quite High
Wound Healing 7 66.08 Quite High
Osteoarthritis 7 5.00 Very Low Very Low Very Low
Pruritus 3 5.00 Very Low Very Low Very Low
Ulcers 2 5.00 Very Low Very Low Very Low
Arthritis 2 5.00 Very Low Very Low Very Low
Injury 2 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
Peptic Ulcer 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
g/ml) was tested for its ability to maintain optimal IGF-1 transcription and translation in cartilage explants and cultured chondrocytes.


Negative_regulation (maintain) of Transcription (transcription) of IGF-1 in cartilage
1) Confidence 0.39 Published 2007 Journal J Inflamm (Lond) Section Abstract Doc Link PMC1971260 Disease Relevance 0.30 Pain Relevance 0.12

General Comments

This test has worked.

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