INT212594

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Context Info
Confidence 0.01
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.83
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

polymerase (Homo sapiens)
Pain Link Frequency Relevance Heat
fibrosis 32 5.00 Very Low Very Low Very Low
alcohol 5 5.00 Very Low Very Low Very Low
depression 2 5.00 Very Low Very Low Very Low
imagery 2 5.00 Very Low Very Low Very Low
drug abuse 1 5.00 Very Low Very Low Very Low
adenocard 1 5.00 Very Low Very Low Very Low
Angina 1 5.00 Very Low Very Low Very Low
Inflammation 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Coronary Heart Disease 1 98.86 Very High Very High Very High
Neuropathic Pain 1 98.48 Very High Very High Very High
Muscle Disease 1 98.24 Very High Very High Very High
Lactic Acidosis 2 98.04 Very High Very High Very High
Toxicity 13 97.62 Very High Very High Very High
Acquired Immune Deficiency Syndrome Or Hiv Infection 114 81.28 Quite High
Hepatitis C Virus Infection 151 64.32 Quite High
Chronic Hepatitis 12 64.00 Quite High
Neutropenia 5 62.32 Quite High
Bacterial Infection 1 22.48 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The interaction can produce mitochondrial toxicity with lactic acidosis, myopathy, neuropathy and cardiomyopathy, all of which are presumably secondary to RBV-dependent increased phosphorylation of didanosine and mitochondrial DNA polymerase (polymerase-?)
Positive_regulation (increased) of Phosphorylation (phosphorylation) of polymerase associated with toxicity, lactic acidosis, neuropathic pain, muscle disease and coronary heart disease
1) Confidence 0.01 Published 2007 Journal Journal of Viral Hepatitis Section Body Doc Link PMC1974798 Disease Relevance 0.83 Pain Relevance 0

General Comments

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