INT212803

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Context Info
Confidence 0.37
First Reported 2007
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 6
Total Number 6
Disease Relevance 0.47
Pain Relevance 0.37

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

phosphatase activity (Rngtt) mRNA processing (Rngtt) nucleus (Rngtt)
nucleotidyltransferase activity (Rngtt)
Rngtt (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 90 99.80 Very High Very High Very High
Inflammation 115 99.60 Very High Very High Very High
Inflammatory response 12 62.52 Quite High
alcohol 1 57.48 Quite High
Analgesic 10 5.00 Very Low Very Low Very Low
Inflammatory mediators 6 5.00 Very Low Very Low Very Low
anticonvulsant 5 5.00 Very Low Very Low Very Low
Paracetamol 5 5.00 Very Low Very Low Very Low
allodynia 5 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 133 99.60 Very High Very High Very High
Death 6 85.52 High High
Sepsis 20 84.48 Quite High
Lifespan 2 70.96 Quite High
Starvation 5 46.40 Quite Low
Injury 6 31.04 Quite Low
Cancer 16 5.00 Very Low Very Low Very Low
Infection 15 5.00 Very Low Very Low Very Low
Necrosis 11 5.00 Very Low Very Low Very Low
Bacterial Infection 9 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Based on this result, in the rest of experiments, the mice were treated with HCE and killed 12 h after the CLP induction to investigate the mechanisms of protection.


Gene_expression (treated) of HCE
1) Confidence 0.37 Published 2008 Journal BMC Complement Altern Med Section Body Doc Link PMC2571085 Disease Relevance 0.37 Pain Relevance 0.09
The cells were exposed to MCE at concentrations of 0.1 and 0.3 mg ml?
Gene_expression (exposed) of MCE
2) Confidence 0.08 Published 2007 Journal Evidence-based Complementary and Alternative Medicine : eCAM Section Body Doc Link PMC1978242 Disease Relevance 0 Pain Relevance 0
Figure 2.Inhibition of LPS-activated cytokines and PGE2 production by MCE.
Gene_expression (production) of MCE associated with cytokine
3) Confidence 0.08 Published 2007 Journal Evidence-based Complementary and Alternative Medicine : eCAM Section Body Doc Link PMC1978242 Disease Relevance 0 Pain Relevance 0.16
As shown in Fig. 1, in the LPS plus MCE groups, the level of NO production decreased in a concentration and time-dependent manner compared with the LPS only group.
Gene_expression (groups) of MCE
4) Confidence 0.08 Published 2007 Journal Evidence-based Complementary and Alternative Medicine : eCAM Section Body Doc Link PMC1978242 Disease Relevance 0 Pain Relevance 0.05
After incubating the cells in the presence of MCE, the viable cells were stained with MTT (0.5 mg ml?
Gene_expression (presence) of MCE
5) Confidence 0.08 Published 2007 Journal Evidence-based Complementary and Alternative Medicine : eCAM Section Body Doc Link PMC1978242 Disease Relevance 0 Pain Relevance 0
MCE was further investigated to determine if it affects the COX-2 expression levels.
Gene_expression (expression) of MCE
6) Confidence 0.07 Published 2007 Journal Evidence-based Complementary and Alternative Medicine : eCAM Section Body Doc Link PMC1978242 Disease Relevance 0.10 Pain Relevance 0.08

General Comments

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