INT212824

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Context Info
Confidence 0.21
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.62
Pain Relevance 1.16

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (WAS) signal transduction (Cnr1) aging (Cnr1)
plasma membrane (Cnr1) protein complex assembly (WAS) signal transducer activity (Cnr1)
Anatomy Link Frequency
neural 1
WAS (Homo sapiens)
Cnr1 (Mus musculus)
Pain Link Frequency Relevance Heat
Cannabinoid receptor 1 100.00 Very High Very High Very High
Nicotine 21 98.18 Very High Very High Very High
Dopamine 13 96.40 Very High Very High Very High
cannabis 24 93.24 High High
Nucleus accumbens 1 86.32 High High
alcohol 25 85.52 High High
withdrawal 8 79.12 Quite High
addiction 61 78.16 Quite High
cocaine 8 32.56 Quite Low
Morphine 4 28.84 Quite Low
Disease Link Frequency Relevance Heat
Targeted Disruption 2 82.80 Quite High
Drug Dependence 9 78.16 Quite High
Cannabis Dependence 9 74.40 Quite High
Nicotine Addiction 19 69.12 Quite High
Alcohol Addiction 7 10.00 Low Low
Schizophrenia 5 5.00 Very Low Very Low Very Low
Mental Disorders 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Specifically, nicotine operates through activation of nicotinic acetylcholine receptor (nAChR) complexes; delta9-THC operates through activation of the neural cannabinoid receptor, CB1R.
THC Positive_regulation (activation) of CB1R in neural associated with cannabinoid receptor and nicotine
1) Confidence 0.21 Published 2007 Journal BMC Genet Section Body Doc Link PMC1978498 Disease Relevance 0.62 Pain Relevance 1.16

General Comments

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