INT21284

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Context Info
Confidence 0.30
First Reported 1990
Last Reported 2005
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 6
Disease Relevance 0.63
Pain Relevance 1.00

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

lyase activity (Pck1) nucleolus (Pck1) nucleus (Pck1)
lipid metabolic process (Pck1) cytoplasm (Pck1)
Anatomy Link Frequency
external 1
Pck1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Morphine 6 99.84 Very High Very High Very High
Action potential 48 93.28 High High
opioid receptor 3 84.12 Quite High
Pain 12 75.24 Quite High
agonist 21 65.44 Quite High
Neurotransmitter 4 54.24 Quite High
adenocard 16 34.96 Quite Low
Enkephalin 1 25.00 Low Low
antagonist 12 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Stroke 4 82.24 Quite High
Nociception 16 77.44 Quite High
Pruritus 4 75.56 Quite High
Pain 12 75.24 Quite High
Bordatella Infection 8 14.48 Low Low
Targeted Disruption 20 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Following treatment of cells with alpha-toxin, both GTP and GTP-gamma-S also enhanced secretion.
Localization (secretion) of GTP
1) Confidence 0.30 Published 1996 Journal Life Sci. Section Abstract Doc Link 8937508 Disease Relevance 0 Pain Relevance 0.40
The ligand-receptor interactions in the presence of GTP were modelled according to the proposed scheme.
Localization (presence) of GTP
2) Confidence 0.21 Published 1990 Journal Biokhimiia Section Abstract Doc Link 2169905 Disease Relevance 0 Pain Relevance 0.15
Therefore, it is also possible that ATP and/or GTP may be released from the ciliates as an intercellular communication strategy.
Localization (released) of GTP
3) Confidence 0.19 Published 2005 Journal Purinergic Signal Section Body Doc Link PMC2096533 Disease Relevance 0.55 Pain Relevance 0.23
As shown in Figure 4, wild type show oscillating plateau depolarizations in a recording solution containing 1.0 µM Ca2+, 0.5 mM Mg2+ and 2.0 mM Na+ when 10 µM GTP is perfused into the recording chamber (Figure 4A).
Localization (perfused) of GTP
4) Confidence 0.18 Published 2005 Journal Purinergic Signal Section Body Doc Link PMC2096533 Disease Relevance 0 Pain Relevance 0.11
Electrophysiological responses to external ATP and GTP
Localization (responses) of GTP in external
5) Confidence 0.18 Published 2005 Journal Purinergic Signal Section Body Doc Link PMC2096533 Disease Relevance 0.08 Pain Relevance 0.12
Chemosensory adaptation to the continued presence of ATP or GTP
Localization (presence) of GTP
6) Confidence 0.18 Published 2005 Journal Purinergic Signal Section Body Doc Link PMC2096533 Disease Relevance 0 Pain Relevance 0

General Comments

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