INT212868

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Context Info
Confidence 0.25
First Reported 2007
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 4
Total Number 4
Disease Relevance 0.44
Pain Relevance 0.25

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell proliferation (LIPA) cell morphogenesis (LIPA) lipid metabolic process (LIPA)
lysosome (LIPA)
LIPA (Homo sapiens)
Pain Link Frequency Relevance Heat
depression 8 99.04 Very High Very High Very High
alcohol 3 87.12 High High
corticosteroid 2 69.80 Quite High
aspirin 2 69.12 Quite High
beta blocker 2 68.20 Quite High
Inflammation 7 30.72 Quite Low
Glutamate 3 5.00 Very Low Very Low Very Low
metalloproteinase 2 5.00 Very Low Very Low Very Low
headache 2 5.00 Very Low Very Low Very Low
imagery 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Depression 8 99.04 Very High Very High Very High
Aging 15 76.44 Quite High
Congenital Anomalies 4 58.68 Quite High
Pheochromocytoma 1 50.72 Quite High
Alzheimer's Dementia 23 50.00 Quite Low
Disease 64 45.20 Quite Low
INFLAMMATION 7 30.72 Quite Low
Toxicity 12 5.00 Very Low Very Low Very Low
Apoptosis 11 5.00 Very Low Very Low Very Low
Amyloid Plaque 9 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
A delay in the offset of melatonin after awakening, when experienced for several weeks or more, has been suspected as a cause of depression [14,41]; however, no correlation was found among current participants between CESD in the laboratory and any lag of aMT6s offset after average home actigraphic wake time.
Gene_expression (participants) of CESD associated with depression
1) Confidence 0.25 Published 2007 Journal J Circadian Rhythms Section Body Doc Link PMC1988787 Disease Relevance 0.18 Pain Relevance 0.05
The CESD was repeated both on the first and last days in the laboratory and one week later, to measure any mood effects of the interventions.
Gene_expression (repeated) of CESD
2) Confidence 0.25 Published 2007 Journal J Circadian Rhythms Section Body Doc Link PMC1988787 Disease Relevance 0.21 Pain Relevance 0.20
The next year, Bhatia and Lal further tested A?
Gene_expression (tested) of Lal
3) Confidence 0.13 Published 2007 Journal Neuropsychiatric Disease and Treatment Section Body Doc Link PMC2656296 Disease Relevance 0.05 Pain Relevance 0
This finding is consistent with the eEPC transcriptome profile that indicated high expression of lysosome enzymes such as lysozyme (LYZ), cathepsins (CTSB, CTSD, CTSH, CTSL1), acid phosphatase (ACP2, ACP5), acid lipase (LIPA), and ?
Gene_expression (expression) of acid lipase
4) Confidence 0.04 Published 2010 Journal BMC Med Genomics Section Body Doc Link PMC2881111 Disease Relevance 0 Pain Relevance 0

General Comments

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