INT212892

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Context Info
Confidence 0.23
First Reported 2007
Last Reported 2007
Negated 0
Speculated 1
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.68
Pain Relevance 0.07

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Fas) aging (Fas) extracellular region (Fas)
plasma membrane (Fas) nucleus (Fas) cytoplasm (Fas)
Anatomy Link Frequency
T cell 2
Fas (Rattus norvegicus)
Pain Link Frequency Relevance Heat
withdrawal 4 77.60 Quite High
Nerve growth factor 1 71.24 Quite High
cytokine 1 5.20 Low Low
anesthesia 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Death 34 99.96 Very High Very High Very High
Injury 94 99.00 Very High Very High Very High
Apoptosis 61 98.64 Very High Very High Very High
Necrosis 1 69.44 Quite High
Cancer 1 69.08 Quite High
Sepsis 49 64.64 Quite High
Congenital Anomalies 1 46.16 Quite Low
Hyperplasia 1 29.08 Quite Low
Alagille Syndrome 2 26.80 Quite Low
Infection 5 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Thus, an interpretation of our data could be that apoptosis in thermal injury rat CD4+ T cell was due to augmentation of AICD (triggered by Fas ligand) despite a deficiency in IL-2 production by thermal injury rat T cells possibly because of an increased AICD sensitivity to IL-2.
Spec (possibly) Negative_regulation (triggered) of Fas Binding (ligand) of in T cell associated with injury, apoptosis and death
1) Confidence 0.23 Published 2007 Journal International Journal of Biological Sciences Section Body Doc Link PMC1989035 Disease Relevance 1.68 Pain Relevance 0.07

General Comments

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