INT212916

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Context Info
Confidence 0.24
First Reported 2007
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 5
Total Number 5
Disease Relevance 1.74
Pain Relevance 0.04

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
B cell 2
[[]] (Mus musculus)
Pain Link Frequency Relevance Heat
Central nervous system 62 73.60 Quite High
imagery 49 50.00 Quite Low
cytokine 26 5.12 Low Low
Spinal cord 29 5.00 Very Low Very Low Very Low
Inflammation 27 5.00 Very Low Very Low Very Low
Neuritis 25 5.00 Very Low Very Low Very Low
Multiple sclerosis 16 5.00 Very Low Very Low Very Low
Sciatic nerve 9 5.00 Very Low Very Low Very Low
tolerance 7 5.00 Very Low Very Low Very Low
chemokine 6 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Neuromyelitis Optica 215 100.00 Very High Very High Very High
Mitral Valve Prolapse 36 99.72 Very High Very High Very High
Chlamydia Infection 7 86.08 High High
Weight Loss 4 82.40 Quite High
Targeted Disruption 38 82.32 Quite High
Reprotox - General 3 1 75.92 Quite High
Infection 116 63.88 Quite High
Histoplasma Infection 1 58.80 Quite High
Immunization 55 58.64 Quite High
Pneumocystis Carinii Infection 2 55.96 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
This has been attributed to the ability IgG2a to interact with all three activating IgG Fc receptors, Fc?
Positive_regulation (activating) of IgG Binding (receptors) of
1) Confidence 0.24 Published 2007 Journal Virol J Section Body Doc Link PMC2186315 Disease Relevance 0.19 Pain Relevance 0
This is the first report that has demonstrated IgG dependent binding of SP-A to a microorganism.
Positive_regulation (demonstrated) of IgG Binding (binding) of
2) Confidence 0.20 Published 2007 Journal PLoS ONE Section Body Doc Link PMC2147053 Disease Relevance 0.17 Pain Relevance 0
40 dilution) for 90 min followed by 60 min with goat anti-rabbit IgG conjugated with 10 nm gold (1?
Positive_regulation (-) of IgG Binding (dilution) of
3) Confidence 0.17 Published 2007 Journal PLoS ONE Section Body Doc Link PMC1991622 Disease Relevance 0.15 Pain Relevance 0
Thus, the “z” peptide increases binding of mouse IgG to cp-MVP-z vaults.
Positive_regulation (increases) of IgG Binding (binding) of associated with mitral valve prolapse
4) Confidence 0.16 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2671841 Disease Relevance 0.89 Pain Relevance 0
At issue is how many of the residues and if their corresponding site chains are exposed "around" the top of AQP4 as potential B cell epitopes required for NMO-IgG binding (Figure 3).
Positive_regulation (required) of NMO-IgG Binding (binding) of in B cell associated with neuromyelitis optica
5) Confidence 0.05 Published 2008 Journal J Neuroinflammation Section Body Doc Link PMC2427020 Disease Relevance 0.33 Pain Relevance 0.04

General Comments

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