INT212921

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Context Info
Confidence 0.12
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.22
Pain Relevance 0.19

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Car2) extracellular space (Car2) lyase activity (Car2)
cytoplasm (Car2)
Car2 (Mus musculus)
Tg(CAG-EGFP)D4Nagy (Mus musculus)
Pain Link Frequency Relevance Heat
imagery 47 89.96 High High
Migraine 1 13.12 Low Low
Sciatic nerve 9 5.00 Very Low Very Low Very Low
tetrodotoxin 2 5.00 Very Low Very Low Very Low
Deep tissue 2 5.00 Very Low Very Low Very Low
Spinal cord 1 5.00 Very Low Very Low Very Low
Neurotransmitter 1 5.00 Very Low Very Low Very Low
nMDA receptor antagonist 1 5.00 Very Low Very Low Very Low
Immobilon 1 5.00 Very Low Very Low Very Low
isoflurane 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Toxicity 1 85.84 High High
Targeted Disruption 20 77.12 Quite High
Apoptosis 4 57.92 Quite High
Headache 1 13.12 Low Low
Cancer 1 12.72 Low Low
Diabetes Mellitus 1 12.40 Low Low
Disease 3 11.28 Low Low
Congenital Anomalies 2 6.80 Low Low
Convulsion 5 5.00 Very Low Very Low Very Low
Epilepsy 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Upon Ca2+ binding, aequorin undergoes a conformational change that oxidizes its substrate coelenterazine (CLZN) and chemiluminescence resonance energy transfer (CRET) to the GFP moiety occurs, with an emission maximum in the green (??
Positive_regulation (Upon) of Ca2 Binding (coelenterazine) of GFP
1) Confidence 0.12 Published 2007 Journal PLoS ONE Section Body Doc Link PMC1991622 Disease Relevance 0.22 Pain Relevance 0.19

General Comments

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