INT212989

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Context Info
Confidence 0.26
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 2.20
Pain Relevance 0.16

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Serpine1) extracellular region (Serpine1)
Anatomy Link Frequency
endothelium 2
Serpine1 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 22 93.44 High High
bradykinin 2 78.48 Quite High
agonist 2 62.56 Quite High
Bioavailability 2 35.36 Quite Low
Bile 2 26.44 Quite Low
metalloproteinase 12 5.00 Very Low Very Low Very Low
cytokine 8 5.00 Very Low Very Low Very Low
Tetrahydrobiopterin 6 5.00 Very Low Very Low Very Low
Inflammatory response 4 5.00 Very Low Very Low Very Low
chemokine 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disorder Of Lipid Metabolism 274 100.00 Very High Very High Very High
Adhesions 36 96.68 Very High Very High Very High
INFLAMMATION 38 93.44 High High
Natriuresis 2 87.16 High High
Hyperlipidemia 6 86.60 High High
Increased Venous Pressure Under Development 6 83.12 Quite High
Stress 2 73.20 Quite High
Cardiovascular Disease 4 66.76 Quite High
Atherosclerosis 20 55.28 Quite High
Disease 2 48.32 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
This correlation may reflect the in vitro inhibitory effect of HDL on tPA and PAI secretion by the endothelium (Ren and Shen 2000).
Negative_regulation (effect) of Localization (secretion) of PAI in endothelium associated with disorder of lipid metabolism
1) Confidence 0.26 Published 2005 Journal Vascular Health and Risk Management Section Body Doc Link PMC1993938 Disease Relevance 1.23 Pain Relevance 0.03
Modulation of hemostasis includes the release of plasminogen activator, tissue factor inhibitor, von Willebrand factor, NO, prostacyclin, TXA2, plasminogen-activator inhibitor-1 (PAI-1), and fibrinogen.
Negative_regulation (inhibitor) of Localization (release) of plasminogen-activator inhibitor-1
2) Confidence 0.19 Published 2005 Journal Vascular Health and Risk Management Section Body Doc Link PMC1993938 Disease Relevance 0.97 Pain Relevance 0.13

General Comments

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