INT212995

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.27
First Reported 2005
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 3.01
Pain Relevance 0.40

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (Vwf) cell adhesion (Vwf) endoplasmic reticulum (Vwf)
proteinaceous extracellular matrix (Vwf)
Anatomy Link Frequency
plasma 2
Vwf (Mus musculus)
Pain Link Frequency Relevance Heat
rheumatoid arthritis 64 99.88 Very High Very High Very High
Inflammation 50 96.04 Very High Very High Very High
cytokine 10 90.20 High High
agonist 1 85.84 High High
Osteoarthritis 9 5.00 Very Low Very Low Very Low
corticosteroid 8 5.00 Very Low Very Low Very Low
cINOD 8 5.00 Very Low Very Low Very Low
spinal inflammation 7 5.00 Very Low Very Low Very Low
Arthritis 7 5.00 Very Low Very Low Very Low
metalloproteinase 6 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Rheumatoid Arthritis 65 99.88 Very High Very High Very High
Adhesions 19 99.56 Very High Very High Very High
Disorder Of Lipid Metabolism 140 98.48 Very High Very High Very High
INFLAMMATION 60 96.04 Very High Very High Very High
Sprains And Strains 1 87.88 High High
Atherosclerosis 26 87.12 High High
General Immunology 1 83.12 Quite High
Atherosclerotic Plaque 8 80.80 Quite High
Targeted Disruption 3 78.72 Quite High
Autoimmune Disease 2 76.08 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Von Willebrand factor (vWF) is another protein expressed by endothelial cells that plays an essential role in platelet adhesion and aggregation; the circulating vWF levels are inversely correlated with plasma HDL (Conlan et al 1993), suggesting that HDL may inhibit vWF production.
Positive_regulation (circulating) of Gene_expression (levels) of vWF in plasma associated with disorder of lipid metabolism and adhesions
1) Confidence 0.27 Published 2005 Journal Vascular Health and Risk Management Section Body Doc Link PMC1993938 Disease Relevance 1.33 Pain Relevance 0.04
Patients with RA have increased serum levels of fibrinogen, von Willebrand factor and tissue plasminogen activator antigen compared with controls and these prothrombotic markers have been shown to predict cardiovascular events in patients with RA (McEntegart et al 2001; Sattar et al 2003).


Positive_regulation (increased) of Gene_expression (levels) of von Willebrand factor associated with rheumatoid arthritis
2) Confidence 0.22 Published 2008 Journal Vascular Health and Risk Management Section Body Doc Link PMC2515420 Disease Relevance 1.61 Pain Relevance 0.36
was seen for vWF where the expression of this gene reached the maximum
Positive_regulation (for) of Gene_expression (expression) of vWF
3) Confidence 0.17 Published 2008 Journal Journal of Biomedicine and Biotechnology Section Body Doc Link PMC2276817 Disease Relevance 0.07 Pain Relevance 0

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox