INT213002

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Context Info
Confidence 0.00
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.02
Pain Relevance 0.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleolus (Trib3) cell adhesion (Scarb1) nucleus (Trib3)
plasma membrane (Scarb1) enzyme binding (Trib3) kinase activity (Trib3)
Scarb1 (Mus musculus)
Trib3 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
cytokine 4 56.88 Quite High
Inflammation 11 25.80 Quite Low
chemokine 2 17.40 Low Low
metalloproteinase 6 5.00 Very Low Very Low Very Low
Tetrahydrobiopterin 3 5.00 Very Low Very Low Very Low
Inflammatory response 2 5.00 Very Low Very Low Very Low
COX2 1 5.00 Very Low Very Low Very Low
Angina 1 5.00 Very Low Very Low Very Low
Bioavailability 1 5.00 Very Low Very Low Very Low
Bile 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disorder Of Lipid Metabolism 137 99.90 Very High Very High Very High
Apoptosis 7 69.52 Quite High
INFLAMMATION 19 55.76 Quite High
Retinoblastoma 1 21.76 Low Low
Adhesions 18 5.00 Very Low Very Low Very Low
Atherosclerosis 10 5.00 Very Low Very Low Very Low
Coronary Artery Disease 6 5.00 Very Low Very Low Very Low
Death 5 5.00 Very Low Very Low Very Low
Necrosis 3 5.00 Very Low Very Low Very Low
Atherosclerotic Plaque 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
A second mechanism has been proposed by Mineo et al (2003), which suggests that HDL via interaction with SR-B1 activate a tyrosine kinase most likely belonging to the src family kinase that phosphorylate both Akt and MAPK.
SR-B1 Binding (interaction) of kinase associated with disorder of lipid metabolism
1) Confidence 0.00 Published 2005 Journal Vascular Health and Risk Management Section Body Doc Link PMC1993938 Disease Relevance 1.02 Pain Relevance 0.03

General Comments

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