INT213037

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Context Info
Confidence 0.19
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.19
Pain Relevance 0.04

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Serpine1) extracellular region (Serpine1)
Anatomy Link Frequency
endothelial cells 2
Hdl1 (Mus musculus)
Serpine1 (Mus musculus)
Pain Link Frequency Relevance Heat
agonist 1 74.08 Quite High
Inflammation 11 5.00 Very Low Very Low Very Low
metalloproteinase 6 5.00 Very Low Very Low Very Low
cytokine 4 5.00 Very Low Very Low Very Low
Tetrahydrobiopterin 3 5.00 Very Low Very Low Very Low
Inflammatory response 2 5.00 Very Low Very Low Very Low
chemokine 2 5.00 Very Low Very Low Very Low
COX2 1 5.00 Very Low Very Low Very Low
Angina 1 5.00 Very Low Very Low Very Low
Bioavailability 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disorder Of Lipid Metabolism 137 100.00 Very High Very High Very High
Adhesions 18 83.52 Quite High
Hyperlipidemia 3 81.48 Quite High
INFLAMMATION 19 50.00 Quite Low
Atherosclerosis 10 5.00 Very Low Very Low Very Low
Apoptosis 7 5.00 Very Low Very Low Very Low
Coronary Artery Disease 6 5.00 Very Low Very Low Very Low
Death 5 5.00 Very Low Very Low Very Low
Necrosis 3 5.00 Very Low Very Low Very Low
Atherosclerotic Plaque 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Of note, when HDL are oxidized, the resulting Ox-HDL have been reported to induce PAI-1 mRNA expression and protein release in endothelial cells via a p38MAPK-dependent pathway that promotes mRNA stabilization (Norata, Banfi, et al 2004).
HDL Positive_regulation (induce) of Gene_expression (expression) of PAI-1 mRNA in endothelial cells associated with disorder of lipid metabolism
1) Confidence 0.19 Published 2005 Journal Vascular Health and Risk Management Section Body Doc Link PMC1993938 Disease Relevance 1.19 Pain Relevance 0.04

General Comments

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