INT213041

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Context Info
Confidence 0.14
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.90
Pain Relevance 0.17

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Vcam1) cell adhesion (Vcam1) plasma membrane (Vcam1)
Anatomy Link Frequency
endothelial cells 2
Hdl1 (Mus musculus)
Vcam1 (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 4 89.20 High High
chemokine 2 60.88 Quite High
Inflammation 11 47.12 Quite Low
Inflammatory response 2 42.12 Quite Low
metalloproteinase 6 17.44 Low Low
Tetrahydrobiopterin 3 5.00 Very Low Very Low Very Low
COX2 1 5.00 Very Low Very Low Very Low
Angina 1 5.00 Very Low Very Low Very Low
Bioavailability 1 5.00 Very Low Very Low Very Low
Bile 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disorder Of Lipid Metabolism 137 100.00 Very High Very High Very High
Adhesions 18 84.68 Quite High
Atherosclerotic Plaque 3 66.48 Quite High
INFLAMMATION 19 50.00 Quite Low
Atherosclerosis 10 48.36 Quite Low
Apoptosis 7 5.00 Very Low Very Low Very Low
Coronary Artery Disease 6 5.00 Very Low Very Low Very Low
Death 5 5.00 Very Low Very Low Very Low
Necrosis 3 5.00 Very Low Very Low Very Low
Increased Venous Pressure Under Development 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Inhibition of VCAM-1 and E-selectin expression on endothelial cells is also induced by reconstituted HDL and depends strongly on the phospholipid composition of reconstituted particles as the inhibitory effects were not exerted by lipid-free apoproteins A-I and A-II (Ashby et al 1998; Calabresi et al 2003; Nofer et al 2003).
HDL Negative_regulation (Inhibition) of Gene_expression (expression) of VCAM-1 in endothelial cells associated with disorder of lipid metabolism
1) Confidence 0.14 Published 2005 Journal Vascular Health and Risk Management Section Body Doc Link PMC1993938 Disease Relevance 0.90 Pain Relevance 0.17

General Comments

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